Neuro

Mystery Quiz- The Answer

June 29, 2012

Vivian Hayashi MD and Robert Smith MD, Mystery Quiz Section Editors

The answer to the mystery quiz is thymoma associated with myasthenia gravis. The clue to the case is the intermittent dysphagia and chewing difficulty. If one considers myasthenia in the differential, then an otherwise grossly normal appearing chest radiograph may be viewed more closely, with attention directed to the upper, anterior mediastinum. The chest radiograph shows the ascending aorta (image 3, arrow); on the lateral film, the retrosternal space, which normally contains air, appears …

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Use it or Lose it- Do cognitive leisure activities protect against the development of Alzheimer’s?

March 30, 2012
Use it or Lose it- Do cognitive leisure activities protect against the development of Alzheimer’s?

By Courtney Cunningham, MD

Faculty Peer Reviewed

As the world population ages, enormous resources will be required to adequately care for persons suffering from Alzheimer’s disease. The disease is the fifth leading cause of death for adults aged 65 years and older, and is estimated to affect 1 in 8 persons in this age group. Despite recent advances, the cause of Alzheimer’s disease is not well understood. The FDA-approved medications in common use—donepezil (Aricept), galantamine (Razadyne), rivastigmine (Exelon), and memantine (Namenda)–help to manage symptoms; however …

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How Should You Choose the Best Anti-platelet Agents for Secondary Stroke Prevention?

February 16, 2012
How Should You Choose the Best Anti-platelet Agents for Secondary Stroke Prevention?

By Demetrios Tzimas, MD

Faculty Peer Reviewed

You are about to discharge a 75-year-old female with hyperlipidemia, hypertension, peripheral vascular disease, who was admitted to the hospital for an ischemic stroke. Being an astute physician, you would like to mitigate this patient’s risk of having a second stroke. But you ask yourself, “with all of the agents available today, what anti-platelet agents should I put this patient on to decrease her risk for a second stroke?”

The etiology of an ischemic stroke, as defined by …

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Dance Therapy in Parkinson’s Disease: Can the Argentine Tango Improve Motor Function?

December 2, 2011
Dance Therapy in Parkinson’s Disease: Can the Argentine Tango Improve Motor Function?

By Neha Jindal

Faculty Peer Reviewed

Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder that affects over 1 million people in the United States. People with PD often demonstrate postural instability, gait difficulties, and impaired functional mobility, which can lead to falls and decreased quality of life. Medical treatments for PD do not fully address gait and balance issues and, consequently, additional approaches are needed. One approach that has recently emerged in clinical studies is the use of dance, particularly the Argentine tango, as …

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Vegetative State 2.0

May 13, 2011
Vegetative State 2.0

By Ivan Saraiva, MD

Faculty Peer Reviewed

 “Mr. Dockery was a police officer in the town of Walden, northwest of Chattanooga, when he was shot in the forehead as he responded to a call on Sept. 17, 1988. He has been motionless and speechless in a nursing home most of the time since then but was recently moved to Columbia Parkridge Medical Center here because of a lung infection. Suddenly, on Monday, he spoke, amazing his family and physicians.” (NY Times, February 17, 1996)

 What …

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Do I have a Concussion?

July 21, 2010
Do I have a Concussion?

By Radhika Sundararajan, M.D., Ph.D

Faculty Peer Reviewed

A healthy 18 year-old female presents to Urgent Care after slipping and falling this morning in the bathroom and hitting her head on the tile floor. She denies any loss of consciousness, vomiting, or current neurological deficits, but does have a mild occipital headache where she struck her head. She has heard a lot about recent research regarding concussions in young athletes and asks if you think she suffered a concussion and what this means for her.…

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Marijuana and Multiple Sclerosis- Half-Baked? The Evidence Behind Cannabinoid Use for the Treatment of Pain and Spasticity in MS Patients

June 3, 2010
Marijuana and Multiple Sclerosis- Half-Baked? The Evidence Behind Cannabinoid Use for the Treatment of Pain and Spasticity in MS Patients

By Maura RZ Madou, MD

Faculty Peer Reviewed

When the New Jersey legislature approved a measure to legalize the use of marijuana for patients with chronic illnesses early this year, multiple sclerosis (MS) patient Charles Kwiatkowski, of Hazlet, N.J., rhetorically asked the New York Times; “The M.S. Society has shown that this drug will help slow the progression of my disease. Why would I want to use anything else?”1 New Jersey was the 14th state in the nation to approve such legislation. Does the drug …

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Alzheimer’s Disease 2.0

May 12, 2010
Alzheimer’s Disease 2.0

Jeffrey Mayne MD

Faculty peer reviewed

Dr. Okonkwo’s post this past summer to PrimeCuts summarized ongoing research in Alzheimer’s Disease (AD), the most common cause of dementia affecting 15 million individuals worldwide and more than 5 million in the United States. It is a disease marked by cognitive deterioration that slowly breaks down one’s ability to perform activities of daily living and leaves individuals unable to care for themselves.

Briefly, the diagnosis of AD is based on clinical criteria and histologic confirmation at death. Based …

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