Polycythemia Vera Presenting as a Hypercoagulable State: What is the Pathophysiologic Role of JAK2 in the Mechanism, Manifestations, and Treatment of the Disease?

August 11, 2010

By Emily Slater

Faculty Peer Reviewed

Mr. R is a 46-year-old man with a past medical history of polycythemia vera on hydroxyurea and chronic hepatitis B and C who presented with acutely worsening left upper-quadrant abdominal pain.  This occurred in the context…

Read the rest of this entry >>
Posted in Heme/Onc

Myths & Realities: Is Shiftwork Tumorgenic?

June 23, 2010

By David Ecker, MD

Faculty Peer Reviewed

Over the last several decades, Westernized countries have become 24-hour societies.  Approximately 21 million workers in the US are on non-standard work shifts, including almost 4 million on regular overnight shifts.[1]  In 1972, Taylor and Pocock…

Read the rest of this entry >>
Posted in Clinical Questions, Heme/Onc, Myths and Realities

Revisiting the USPSTF Breast Cancer Screening Guidelines: Ethics, and Patient Responsibilities

May 6, 2010

David Shabtai

Faculty Peer Reviewed

 In a bold move, the U.S. Preventive Services Task Force recently changed their breast cancer screening guidelines – recommending beginning screening at age 50 and even then only every other year until age 75. Bold, because the…

Read the rest of this entry >>
Posted in Class Act, Ethics, Heme/Onc

Chief of Service Rounds: Should You Always Stop Anticoagulating a Bleeding Patient?

January 20, 2010

bellevueChief-of-service rounds is a new feature of Clinical Correlations.  Here we summarize Bellevue Hospital’s Chief of Service Rounds moderated by the Chief of Medicine, Nate Link, MD.  This multidisciplinary bimonthly conference focuses on a case that presents a diagnostic or…

Read the rest of this entry >>
Posted in Chief of Service Rounds, GI, Heme/Onc

Prostate Cancer Screening: Where Do We Stand Now?

December 9, 2009

20080311-bellevue-hospital-03Annery Garcia

Prostate cancer is the second most common cancer in western men and the second leading cause of cancer-related deaths in men in the U.S.1 In 2007 approximately 218,890 men were diagnosed with prostate cancer, and it is expected that…

Read the rest of this entry >>
Posted in Heme/Onc

Breaking News: Begin Cervical Cancer Screening at 21 Says ACOG

November 20, 2009

800px-ca_in_situ2c_cervix_2Joshua Strauss, MD

In the second decision of its kind and magnitude in a matter of days, a major medical group has again recommended cutting back on cancer screening for women.  On the heels of Monday’s USPSTF release on reducing mammography,…

Read the rest of this entry >>
Posted in Breaking News, Heme/Onc

Breaking News: Initiate Mammography Screening at 50, not 40, Says USPSTF.

November 17, 2009

mammogram_showing_breast_cancerAalok Turakhia, MD

As the debate over when to begin screening mammography in women rages on, the United States Prevention Service Task Force (USPSTF) added fuel to the fire by releasing a new recommendation statement in the November 17th issue of…

Read the rest of this entry >>
Posted in Breaking News, Heme/Onc

PrimeCuts: This Week in the Journals

September 14, 2009

thebear1Michael Ford MD

Faculty Peer Reviewed

Last spring, The New York Times published a series of articles that examined the status of “the War on Cancer,” initiated some 40 years ago by then president Richard Nixon[1]. The halting pace of this war was made…

Read the rest of this entry >>
Posted in Heme/Onc, PrimeCuts

Myths and Realities: Do Power Lines Cause Cancer?

May 20, 2009

powerlines

Aditya Mattoo MD

Faculty Peer Reviewed

Prompted by personal experience, I thought I would explore the alleged causative role of power lines in hematologic malignancies for the next installment of Myths and Realities. In recent years, two close family friends living at…

Read the rest of this entry >>
Posted in Heme/Onc, Myths and Realities

The Skinny on Cachexia…Can it be Treated?

April 22, 2009

megace-2Michael T. Tees, MD, MPH

On the wards and in the clinic, the physician is frequently presented with a patient with a decreased appetite and alarming weight loss. The patient is likely frustrated with their own fraility, the family is upset…

Read the rest of this entry >>
Posted in Clinical Questions, Heme/Onc, Nutrition

Clinical Questions: How do you dose argatroban?

April 16, 2009

argatroban

Frederick Gandolfo, MD

Case: An 85 year-old woman admitted to the hospital with pneumonia and after a prolonged hospital course developed heparin-induced thrombocytopenia (HIT). She is currently being treated with argatroban and her platelet counts are recovering. You are the covering…

Read the rest of this entry >>
Posted in Clinical Questions, Heme/Onc

Prostate Cancer and Antioxidants

February 25, 2009

Commentary by Christopher Tully MD, PGY-1

Faculty Peer Reviewed

An apple a day. . . keeps the prostate cancer away? While it is an overstatement to say that an apple can prevent cancer, the notion of taking “something” to prevent cancer initiation and…

Read the rest of this entry >>
Posted in Heme/Onc, Urology