Rheumatology

Diagnostic Dilemma-Poststreptococcal Reactive Arthritis in a Pregnant Woman

September 18, 2013
Diagnostic Dilemma-Poststreptococcal Reactive Arthritis in a Pregnant Woman

By Bryan Stierman and Todd Cutler, MD

Faculty Peer Reviewed

Case Presentation

A 35-year-old Hispanic woman presented to the emergency room with severe joint pain and swelling for one week.

The patient had a history of hypothyroidism and hepatitis C which was treated with interferon therapy two years prior. She was recently discovered to be pregnant and, at the time of presentation, was in her tenth week of pregnancy. Three weeks prior to admission she developed a sore throat. She saw an outside care provider…

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Gout: A Disease of the Blessed or a Blessing in Disguise?

June 8, 2012
Gout: A Disease of the Blessed or a Blessing in Disguise?

By Krithiga Sekar

Faculty Peer Reviewed

“The patient goes to bed and sleeps quietly until about two in the morning when he is awakened by a pain which usually seizes the great toe, but sometimes the heel, the calf of the leg or the ankle… so exquisitely painful as not to endure the weight of the clothes nor the shaking of the room from a person walking briskly therein.”

—Thomas Sydenham  (1683)

Gout, an excruciatingly painful but relatively benign form of arthritis in the…

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FROM THE ARCHIVES: How Do You Diagnose Polymyalgia Rheumatica?

March 1, 2012
FROM THE ARCHIVES: How Do You Diagnose Polymyalgia Rheumatica?

Please enjoy this post from the archives dated August 12, 2009

By Eve Wadsworth MD

Faculty Peer Reviewed

Polymyalgia rheumatica (PMR) is a condition that resembles several different disorders including osteoarthritis and can be difficult to diagnose. In addition to osteoarthritis, PMR can resemble conditions as diverse as depression, fibromyalgia, myopathic drug reactions, and malignancy. PMR, however, can be associated with dangerous consequences, namely blindness, and is responsive to well-established treatment regimens. As such, familiarity with PMR’s presentation and its unique features is critical so…

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Systemic Lupus Erythematosus and Premature Coronary Artery Disease

July 14, 2011
Systemic Lupus Erythematosus and Premature Coronary Artery Disease

Please enjoy this post from the Clinical Correlations archives first posted June 17, 2009

Ishmeal  Bradley MD

Faculty Peer Reviewed

Ms. W is a 35 yo woman with a history of systemic lupus erythematosus diagnosed 10 years ago. Her only medications are hydroxychloroquine and prednisone for occasional disease flares. She is otherwise healthy. She has no known personal or family history of cardiac disease or stroke, but does smoke ½ pack of cigarettes per day. Currently, she denies any chest pain, shortness of breath, urinary…

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ANCA and Small-Vessel Vasculitis

July 7, 2011
ANCA and Small-Vessel Vasculitis

By Eugene Friedman, Class of 2012

Faculty Peer Reviewed

The discovery of anti-neutrophil cytoplasmic antibodies (ANCA) was a serendipitous finding. In 1982, Davies and colleagues published a report detailing their discovery of antibodies that specifically localized to the cytoplasm of neutrophils in patients with necrotizing glomerulonephritis and small-vessel vasculitis–antibodies that disappeared after immunosuppressive therapy and reappeared with disease recurrence. Two years later, Hall and colleagues confirmed this observation , paving the way for the 1985 Lancet article where van der Woude and colleagues…

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From the Archives: Myths and Realities: Does the Weather Really Affect Arthritis?

March 3, 2011
From the Archives: Myths and Realities: Does the Weather Really Affect Arthritis?

Please enjoy this post from the Clinical Correlations archives first posted March 19, 2009

Aditya Mattoo MD

Faculty Peer Reviewed

For our first post, I wanted to address the age old belief that changes in the weather can affect arthritis pain. Since the time of Hippocrates, who wrote about the effects of hot and cold winds on people’s health, this topic has been debated. Even Osler suggested in 1892 that arthritis sufferers of wealth vacation…

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Diseases 2.0: Rheumatoid Arthritis

September 18, 2009
Diseases 2.0: Rheumatoid Arthritis

Diseases 2.0 – Bringing you the latest updates on disease pathophysiology and treatment

Rachana Jani MD

Faculty peer reviewed

Rheumatoid arthritis is a well-recognized but enigmatic disease afflicting the lives of thousands of individuals each year. The mysterious nature of RA has become increasingly uncovered as research has mapped various pathways of cytokine production and interleukin activation. However, in practice, we use clinical criteria to diagnose RA and evaluate the effectiveness of these new therapies.Though soon to…

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Class Act: How Do You Diagnose Polymyalgia Rheumatica?

August 12, 2009
Class Act: How Do You Diagnose Polymyalgia Rheumatica?

Eve Wadsworth MD

Faculty Peer Reviewed

Polymyalgia rheumatica (PMR) is a condition that resembles several different disorders including osteoarthritis and can be difficult to diagnose. In addition to osteoarthritis, PMR can resemble conditions as diverse as depression, fibromyalgia, myopathic drug reactions, and malignancy. PMR, however, can be associated with dangerous consequences, namely blindness, and is responsive to well-established treatment regimens. As such, familiarity with PMR’s presentation and its unique features is critical so as to avoid serious complications that…

Read more »

Systemic Lupus Erythematosus and Premature Coronary Artery Disease

June 17, 2009
Systemic Lupus Erythematosus and Premature Coronary Artery Disease

Ishmeal  Bradley MD

Faculty Peer Reviewed

Ms. W is a 35 yo woman with a history of systemic lupus erythematosus diagnosed 10 years ago. Her only medications are hydroxychloroquine and prednisone for occasional disease flares. She is otherwise healthy. She has no known personal or family history of cardiac disease or stroke, but does smoke ½ pack of cigarettes per day. Currently, she denies any chest pain, shortness of breath, urinary symptoms, lower extremity edema, or menstrual irregularities, but does…

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Grand Rounds: The Role of Omega-3 fatty Acids in Rheumatoid Arthritis

May 6, 2009
Grand Rounds: The Role of Omega-3 fatty Acids in Rheumatoid Arthritis

Michael Owen MD

Please also see the clinical vignette presented before Grand Rounds on the 15th of April.

Grand rounds on April 15th was presented by Dr. Joel Kremer, Pfaff Family Professor of Medicine at Albany Medical College and Director of Research at the Center for Rheumatology. Dr. Kremer informed the NYU community about the role of omega-3 fatty acid supplementation in rheumatoid arthritis.

Dr. Kremer began with an overview of fatty…

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Myths and Realities: Does the Weather Really Affect Arthritis?

March 19, 2009
Myths and Realities: Does the Weather Really Affect Arthritis?

Welcome to the first installment of Myths and Realities! With each post we hope to tackle some of the longstanding myths often perpetuated by patients and physicians alike. Through literature reviews we will attempt to validate or debunk these beliefs in an evidence-based manner. We hope you enjoy (and learn a little bit)!

Commentary by Aditya Mattoo MD PGY-3

Faculty Peer Reviewed

For our first post, I wanted to address the age old belief that changes in the weather can affect arthritis pain.…

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Grand Rounds: Gout and Hyperuricemia: Some New Thoughts About an Old Disease

March 11, 2009
Grand Rounds: Gout and Hyperuricemia: Some New Thoughts About an Old Disease

Commentary by Deena Altman MD, PGY-2

Please also see the clinical vignette presented before grand rounds on February 18th.

At medical grand rounds on February 18, 2009, our very own Dr. Pillinger gave a unique overview of the history, pathogenesis, and new theories on an ancient and increasingly common disease, gout.

His talk began with a depiction of gout throughout the ages. Podagra was first described in 2600 BC, with the first urate crystals being recognized in 1961 by…

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