Rheumatology

Diseases 2.0: Rheumatoid Arthritis

September 18, 2009
Diseases 2.0: Rheumatoid Arthritis

Diseases 2.0 – Bringing you the latest updates on disease pathophysiology and treatment

Rachana Jani MD

Faculty peer reviewed

Rheumatoid arthritis is a well-recognized but enigmatic disease afflicting the lives of thousands of individuals each year. The mysterious nature of RA has become increasingly uncovered as research has mapped various pathways of cytokine production and interleukin activation. However, in practice, we use clinical criteria to diagnose RA and evaluate the effectiveness of these new therapies.Though soon to be updated, the American College of Rheumatology (ACR) …

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Class Act: How Do You Diagnose Polymyalgia Rheumatica?

August 12, 2009
Class Act: How Do You Diagnose Polymyalgia Rheumatica?

Eve Wadsworth MD

Faculty Peer Reviewed

Polymyalgia rheumatica (PMR) is a condition that resembles several different disorders including osteoarthritis and can be difficult to diagnose. In addition to osteoarthritis, PMR can resemble conditions as diverse as depression, fibromyalgia, myopathic drug reactions, and malignancy. PMR, however, can be associated with dangerous consequences, namely blindness, and is responsive to well-established treatment regimens. As such, familiarity with PMR’s presentation and its unique features is critical so as to avoid serious complications that can result from a delayed or …

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Systemic Lupus Erythematosus and Premature Coronary Artery Disease

June 17, 2009
Systemic Lupus Erythematosus and Premature Coronary Artery Disease

Ishmeal  Bradley MD

Faculty Peer Reviewed

Ms. W is a 35 yo woman with a history of systemic lupus erythematosus diagnosed 10 years ago. Her only medications are hydroxychloroquine and prednisone for occasional disease flares. She is otherwise healthy. She has no known personal or family history of cardiac disease or stroke, but does smoke ½ pack of cigarettes per day. Currently, she denies any chest pain, shortness of breath, urinary symptoms, lower extremity edema, or menstrual irregularities, but does report occasional mild joint pain …

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Grand Rounds: The Role of Omega-3 fatty Acids in Rheumatoid Arthritis

May 6, 2009
Grand Rounds: The Role of Omega-3 fatty Acids in Rheumatoid Arthritis

Michael Owen MD

Please also see the clinical vignette presented before Grand Rounds on the 15th of April.

Grand rounds on April 15th was presented by Dr. Joel Kremer, Pfaff Family Professor of Medicine at Albany Medical College and Director of Research at the Center for Rheumatology. Dr. Kremer informed the NYU community about the role of omega-3 fatty acid supplementation in rheumatoid arthritis.

Dr. Kremer began with an overview of fatty acid biochemistry including saturated, mono-unsaturated, and polyunsaturated fatty acids. Omega-3 fatty acids are …

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Myths and Realities: Does the Weather Really Affect Arthritis?

March 19, 2009
Myths and Realities: Does the Weather Really Affect Arthritis?

Welcome to the first installment of Myths and Realities! With each post we hope to tackle some of the longstanding myths often perpetuated by patients and physicians alike. Through literature reviews we will attempt to validate or debunk these beliefs in an evidence-based manner. We hope you enjoy (and learn a little bit)!

Commentary by Aditya Mattoo MD PGY-3

Faculty Peer Reviewed

For our first post, I wanted to address the age old belief that changes in the weather can affect arthritis pain. Since the …

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Grand Rounds: Gout and Hyperuricemia: Some New Thoughts About an Old Disease

March 11, 2009
Grand Rounds: Gout and Hyperuricemia: Some New Thoughts About an Old Disease

Commentary by Deena Altman MD, PGY-2

Please also see the clinical vignette presented before grand rounds on February 18th.

At medical grand rounds on February 18, 2009, our very own Dr. Pillinger gave a unique overview of the history, pathogenesis, and new theories on an ancient and increasingly common disease, gout.

His talk began with a depiction of gout throughout the ages. Podagra was first described in 2600 BC, with the first urate crystals being recognized in 1961 by polarizing microscope. While noting that Charles …

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Real Time Clinical Question: Rheumatology

February 13, 2009
Real Time Clinical Question: Rheumatology

Commentary by Jon-Emile Kenny MD, PGY- 2 

Faculty Peer Reviewed

At morning report, the case of a 55 F with known dermatomyositis (DM), and interstitial lung involvement who had presented to the hospital with increasing dyspnea was presented.  The discussion of the case opened with the cardinal manifestations of DM including proximal muscle weakness as diagnosed with EMG, cutaneous manifestations such as the heliotrope rash, the shawl sign, Gottron’s papules, Reynaud’s, and ‘Mechanics Hand’, and the systemic manifestations such as interstitial lung disease.

We then …

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Class Act: Is there clinical evidence for the use of chondroitin sulfate in the treatment of osteoarthritis?

October 17, 2008
Class Act: Is there clinical evidence for the use of chondroitin sulfate in the treatment of osteoarthritis?

Class act is a feature of Clinical Correlations written by NYU 3rd and 4th year medical students. Prior to publication, each commentary is thoroughly reviewed for content by a faculty member.

Commentary by Jillian Borman, MS-4, Reviewed by Svetlana Krasnokutsky, MD, Clinical Instructor, NYU Department of Medicine

Osteoarthritis (OA) is one of the most common causes of joint pain in the aging population. The pain of OA, which is generally worsened with joint use and alleviated with rest, is typically described as a deep ache …

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