Clinical Questions

Why Are Asthma Patients Noncompliant With Their Inhalers?

January 11, 2012
Why Are Asthma Patients Noncompliant With Their Inhalers?

By Kristen Mattei

Faculty Peer Reviewed

I distinctly remember being 9 years old, sitting in my doctor’s office after a cold left me struggling for breath, doubled over and wheezing, when he told me that I had asthma. At first I didn’t believe the diagnosis, despite the fact that the albuterol inhaler he had given me was like a breath of life after running suicides on the soccer field. I wasn’t sick or weak! My father insisted I needed to “build my breath up,” and…

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Does Perioperative Smoking Cessation Improve outcomes?

January 6, 2012
Does Perioperative Smoking Cessation Improve outcomes?

By Benjamin Wu, MD

Faculty Peer Reviewed

Mr. T is a 53-year-old man, with history significant for cholelithiasis. He decides to have an elective cholecystectomy after years of biliary colic. Mr. T is an active smoker and wanted to know if he should stop smoking prior to surgery?

Smoking is associated with adverse outcomes in surgery, however debate continues regarding the safety of perioperative smoking cessation. The current understanding of perioperative smoking cessation follows that smokers who stop smoking close to surgery have a higher…

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What Is the Significance of Monoclonal Gammopathy of Undetermined Significance (MGUS)?

December 22, 2011
What Is the Significance of Monoclonal Gammopathy of Undetermined Significance (MGUS)?

By Maryann Kwa, MD

Faculty Peer Reviewed

Clinical Case:

A.D. is a healthy 65-year-old African American male with no prior medical history who presents to his primary care physician for an annual check up. He feels well and has no complaints. Physical exam is normal. Common laboratory tests are ordered which are significant for an elevated total serum protein with normal albumin. A serum protein electrophoresis (SPEP) is then performed. The patient is found to have a monoclonal protein (M protein) of 12 g/L, IgG…

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Is There Really Any Role For Steroids In Acute Alcoholic Hepatitis?

December 8, 2011
Is There Really Any Role For Steroids In Acute Alcoholic Hepatitis?

By Keri Herzog, MD

Faculty Peer Reviewed

The patient is a 48-year-old male with a history of heavy alcohol use (he drinks about 1 pint of vodka daily) who presented to the hospital when he noticed that he had become increasingly jaundiced. The patient was hemodynamically stable on admission and afebrile, with jaundice and scleral icterus on exam. Laboratory data was significant for a total bilirubin of 6.6, an INR of 2.3, AST of 83, ALT 72, and a Maddrey’s discriminant function (MDF) that was…

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Dance Therapy in Parkinson’s Disease: Can the Argentine Tango Improve Motor Function?

December 2, 2011
Dance Therapy in Parkinson’s Disease: Can the Argentine Tango Improve Motor Function?

By Neha Jindal

Faculty Peer Reviewed

Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder that affects over 1 million people in the United States. People with PD often demonstrate postural instability, gait difficulties, and impaired functional mobility, which can lead to falls and decreased quality of life. Medical treatments for PD do not fully address gait and balance issues and, consequently, additional approaches are needed. One approach that has recently emerged in clinical studies is the use of dance, particularly the Argentine tango, as…

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Does Culturing the Catheter Tip Change Patient Outcomes?

November 17, 2011
Does Culturing the Catheter Tip Change Patient Outcomes?

By Todd Cutler, MD

Faculty Peer Reviewed

An 82-year-old man is admitted to the intensive care unit with fevers, hypoxic respiratory failure and hypotension. He is intubated and resuscitated with intravenous fluids. A central venous catheter is placed via the internal jugular vein. A chest x-ray showed a right lower lobe infiltrate and he is treated empirically with antibiotics for pneumonia. Blood cultures grow out S. pneumoniae. After four days he is successfully extubated. The night following extubation, the patient has a fever of 100.8…

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The Diagonal Earlobe Crease: Historical Trivia or a Useful Sign of Coronary Artery Disease?

November 2, 2011
The Diagonal Earlobe Crease: Historical Trivia or a Useful Sign of Coronary Artery Disease?

Nicholas Mark, MD & Sarah Buckley, MD

Faculty Peer Reviewed

 Background

Publius Aelius Hadrianus, better known as Hadrian, emperor of Rome (117-138 CE), traveler, warrior, and lover of all things Greek, fell ill at the age of 60. He developed progressive edema and episodic epistaxis, fell into a depression soothed by rich food and drink, and succumbed to death within 2 years. The exact cause of Hadrian’s death–whether by heart failure, glomerulonephritis, or even hereditary hemorrhagic telangiectasia–has been a topic of debate among paleopathologists. It was…

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Should Women Be Screened For Abdominal Aortic Aneurysms?

October 26, 2011
Should Women Be Screened For Abdominal Aortic Aneurysms?

By Michael Boffa

Faculty Peer Reviewed

Laura K. sits in the office of her cardiologist waiting for the results of her follow-up aorto-iliac duplex scan. Six months ago, Laura had an endostent placed in her abdominal aorta after a 5.2 cm x 5.4 cm abdominal aortic aneurysm (AAA) was discovered.  Though she has recently quit, Laura, now 70, smoked for a large portion of her life. Her advanced age and smoking put her at increased risk of suffering a potentially life-threatening aortic aneurysm rupture. …

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Bariatric Surgery: A Cure for Diabetes?

October 20, 2011
Bariatric Surgery: A Cure for Diabetes?

By Amy Dinitz

 Faculty Peer Reviewed

 The lifetime risk of developing diabetes for persons born in 2000 is around 35% and the NHANES database has suggested a greater than fourfold increase in prevalence over the last three generations.  While bariatric surgery has become the most effective treatment for obesity, it has also been found to be an extremely effective treatment for type 2 diabetes.  It was initially thought that the weight loss experienced by patients after bariatric surgery was responsible for improved glycemic control.  However,…

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Breast Self-Examination: Worth the Effort?

October 5, 2011
Breast Self-Examination: Worth the Effort?

By Katherine Husk

Faculty Peer Reviewed

A healthy 40-year-old woman comes into your office for a routine health exam.  After you have performed a clinical breast exam, she asks you whether she should be examining her breasts on her own at home… 

Breast self-exam (BSE) seems sensible. Empowering a patient to develop a sense of a personal norm could allow for easier recognition of breast changes, and could perhaps lead to earlier evaluation by a medical professional. There is a great deal of controversy, however,…

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Intercessory Prayer: What Do Sneezes and Prayers Have in Common?

September 21, 2011
Intercessory Prayer: What Do Sneezes and Prayers Have in Common?

By Alon Mass

Faculty Peer Reviewed

 The overlap between religion and medicine is ancient. On a recent medical volunteer trip to India I met a medical student who proudly wore a school sweatshirt with the saying: In God we trust. The rest we dominate.

This arrogant approach is probably uncommon, but praying to God for healing–self or intercessory–is not. 

Intercessory prayer is a form of prayer conducted by a group or individual who petitions a god on behalf of another individual in…

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Does Medical School Erode Student Empathy?

August 10, 2011
Does Medical School Erode Student Empathy?

By Nandini Govil

Faculty Peer Reviewed

 Empathy is an elusive concept, espoused by many as an integral component of effective doctoring. In the medical literature, empathy is defined as a physician’s ability to recognize and validate a patient’s experiences and perspectives,  and to convey this understanding back to the patient. A firm distinction is drawn between sympathy (an emotional attribute) and empathy (a cognitive skill that can be modeled, taught, and assessed).

 Research indicates that physician empathy results in better patient compliance and  outcomes,…

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