PrimeCuts

Primecuts-This Week in the Journals

June 27, 2011
Primecuts-This Week in the Journals

By Saleem Ali, MD

Faculty Peer Reviewed

First up this week is a new study in NEJM about a new drug called bardoxalone methyl, currently being studied to treat CKD in patients with diabetes. This drug is an antioxidation inflammation modulator. It activates the Keap1-Nrf pathways that are important in modulating oxidative stress on the kidney. Patients were given placebo vs. various dosages of bardoxalone. Their GFR were measured every 4 weeks for a total of 52 weeks.  The study showed a significant rise …

Read more »

Primecuts – This Week In The Journals

June 20, 2011
Primecuts – This Week In The Journals

By Megha Shah, MD

Faculty Peer Reviewed

Captain America has a shield, Thor has a hammer, the Green Lantern has a power ring, and we…well, we have our stethoscopes. While Dr. Superhero may not be the next big blockbuster to hit the movie theaters this summer, we as healthcare professionals certainly do our share in battling many of the villains- cardiac disease, dementia, cancer – that threaten us everyday. And while the X-Men might turn to Professor X for guidance and wisdom, you can always …

Read more »

Primecuts – This Week In The Journals

June 13, 2011
Primecuts – This Week In The Journals

By Christopher Schultz, MD

Faculty Peer Reviewed

News about the devastating tornado that flattened Joplin, MO had begun to fall from the headlines until reports of a relatively rare fungal infection in a surprisingly large number of people emerged this week. Mucormycosis is generally spread via puncture wounds or through the air, not person-to-person. It mainly inflicts its woes on those with impaired immune systems. More troubling was the recent E. coli outbreak in Germany which caused 31 deaths and sickened thousands. Health officials …

Read more »

Primecuts – This Week In The Journals

June 6, 2011
Primecuts – This Week In The Journals

By Aviva Regev

Faculty Peer Reviewed

Hello?  Can you hear me now?  Making big headlines this week is a topic that is likely to hit very close to home for many of our readers, as well as people from all walks of life, across the globe.  The World Health Organization (WHO)/International Agency for Research on Cancer (IARC) published a press release classifying radiofrequency electromagnetic fields – those emitted by cellular phones – as “possibly carcinogenic to humans.”  The IARC found cell phone use to …

Read more »

Primecuts – This Week In The Journals

May 31, 2011
Primecuts – This Week In The Journals

By Varun Verma, MD

Faculty Peer Reviewed

Our thoughts and prayers this week are with the victims of Joplin, Missouri, who struggle to rebuild their lives after being struck with one of the deadliest tornadoes in US history. Although we can do little about unpredictable natural occurrences, this week’s medical journals reveal some promising interventions that may help us improve the health of our patients.

The New York Times highlighted the National Institutes of Health clinical trial AIM HIGH, the results of which call …

Read more »

Primecuts – This Week In The Journals

May 23, 2011
Primecuts – This Week In The Journals

By Vincent Santillo, MD

Faculty Peer Reviewed

The press and the public that devours it thrive on exciting headlines of misfortune and misdeeds. After a week filled with powerful men acting terribly, it was a relief to see the big new positive news stories — “Paralyzed now walk” and “Coffee Protects from Cancer”. Bring on the caffeine and science fiction as we take a look at some of the more interesting articles appearing this week. The New York Times excitedly announces that “a paralyzed man …

Read more »

Primecuts – This Week In The Journals

May 16, 2011
Primecuts – This Week In The Journals

By Matthew Ingham, MD

Faculty Peer Review

Change to the established order, in politics as in medicine, is a slow and painstaking process. Across the Middle East and particularly in Syria and Libya, the initial excitement and intensity of popular uprisings has faded as opposition groups dig in to continue their threat to existing regimes. A series of articles in the major medical journals this week present evidence that similarly threatens to overturn our current way of doing things, but, as in politics, change is …

Read more »

Primecuts – This Week In The Journals

May 9, 2011
Primecuts – This Week In The Journals

By Megha Shah, MD

Faculty Peer Reviewed

This week we were witness to the courage, perseverance, and ultimately, the triumph of the American military in the ongoing efforts against terrorism. In a similar, albeit physically less threatening manner, scientists, researchers, and physicians work everyday to prevent and eradicate disease. In this week’s Primecuts, we celebrate those who fight to eliminate threats to our well-being and bring you the latest in the scientific headlines.

The New York Times reported on a study published in the New …

Read more »

Primecuts – This Week In The Journals

May 2, 2011
Primecuts – This Week In The Journals

By Ian Fagan, MD 

Faculty Peer Reviewed

Is springtime the season for love? Take a look outside—the birds are chirping, the bees are buzzing, the flowers are blooming. There are strangers mingling in the parks, couples out and about holding hands. The energy is palpable and signs of blossoming love are abundant. Even this week’s journals couldn’t avoid matters of the heart.

For instance, the New England Journal of Medicine published an article looking at coronary-artery bypass grafting (CABG) in patients with left ventricular dysfunction. …

Read more »

Primecuts – This Week In The Journals

April 25, 2011
Primecuts – This Week In The Journals

By Keri Herzog, MD

Faculty Peer Reviewed 

Amidst tornadoes in the southeast, wildfires in the southwest, and flooding in the northeast, it is often impossible to predict when or who may be affected by the weather that has been afflicting our nation. As we pick up the pieces, and take some control over our lives, it is comforting to know that this week the journals have focused on how we can best utilize our medical and scientific resources to be able to identify and change …

Read more »

Primecuts – This Week In The Journals

April 18, 2011
Primecuts – This Week In The Journals

By Melissa Mroz, MD

Faculty Peer Reviewed

Protection was the theme in journals for the second week of April.  The New York Times and NEJM both published the results from the VA initiative to prevent MRSA infections .  This initiative was implemented in 2007 throughout the VA hospitals.  The “MRSA bundle” included nasal surveillance of all patients on admission, transfer and discharge, contact precautions for colonized and infected patients, hand hygiene, and strict infection control.  The rate of MRSA infection was calculated in events per …

Read more »

Primecuts – This Week In The Journals

April 11, 2011
Primecuts – This Week In The Journals

By Demetrios Tzimas, MD

Faculty Peer Reviewed

Our cousins across the Atlantic are feeling the economic sting: in Great Britain they will be implementing market-style changes to their health care system and moving away from a system of complete central control.  As reported in the New England Journal of Medicine, the British government is instituting financial incentives to improve healthcare for all British citizens through payment reform, shifting control of hospitals to local communities, and giving patients a greater role in decisions about their care.  …

Read more »