PrimeCuts

Primecuts – This Week in the Journals

October 9, 2017
Primecuts – This Week in the Journals

By Joanne Bruno, MD/PhD

Peer Reviewed 

There’s finally starting to be a bit more of a chill in the air, which can only mean one thing – pie season is finally here! While this time of year is rife with celebration and gluttony, it is also a time to give back to those in need. This is especially relevant this year given that Puerto Rico is still reeling from the devastation left by Hurricane Maria and Las Vegas just experienced one of the worst mass …

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Primecuts – This Week in the Journals

October 2, 2017
Primecuts – This Week in the Journals

By Kumar Vasudevan, MD

Peer Reviewed

With October beginning and the weather starting to change, the season for apple picking, Pumpkin Spice Lattes, and football also commences. However, with all the joys of fall, we also begin flu season and prepare for all the complications that it brings.  With this in mind, we turn to the medical literature which searches for novel treatments for this deadly illness.

Oseltamivir, Amantadine and Ribavirin Combination Antiviral Therapy versus Oseltamivir Monotherapy for the Treatment of Influenza

The flu is …

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Primecuts – This Week in the Journals

September 18, 2017
Primecuts – This Week in the Journals

By Alvaro F. Vargas P. M.D

Peer Reviewed

As the world and the United States recover from disasters such as storms the size of a country , record-breaking earthquakes , and hundreds of millions of data breaches , let us force ourselves to turn our attention to the comforts of data with this week’s Primecuts.

SPRINT re-revisited: intensive BP control increases CKD events but still saves lives

The well-referenced SPRINT trial (5), continues to be prominently featured in the literature. Three weeks ago a NEJM …

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Primecuts – This Week in the Journals

September 6, 2017
Primecuts – This Week in the Journals

By Rushad Dordi, MD

Peer Reviewed

This week’s Primecuts details four examples of novel methodologies for treating common diseases. We begin first with a study repurposing an anti-inflammatory therapeutic for the treatment of atherosclerosis, and move onto a new targeted gene therapy for malignant mesothelioma. Finally, we touch on using probiotics to modify peanut allergies, based on a novel understanding of immunogenicity, and using the immune system to assist regulation in type 1-diabetes. Together, these studies show the power of creative thinking in the scientific …

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Primecuts – This Week in the Journals

August 29, 2017
Primecuts – This Week in the Journals

By Scarlett Murphy, MD

Peer Reviewed

American attention shifted away from challenging national conversations in the wake of Charlottesville towards the sky this past Monday, when a total solar eclipse traversed the entire US mainland for the first time since 1918 (1).  Although we missed out on the breath-taking experience of totality, New Yorkers still enjoyed a 72% partial eclipse (2).

President Trump held a special rally in Arizona, where he criticized the media for propagating his comments about Charlottesville that seemed to some to …

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Primecuts – This Week in the Journals

August 21, 2017
Primecuts – This Week in the Journals

By Andrew Armanious, MD

Peer Reviewed

This past week, President Trump decided to part ways with White House Chief Strategist Steve Bannon (1). Bannon was a controversial and blunt-spoken political figure who influenced President Trump on many of his contentious campaign decisions. Bannon will be returning to his prior position of executive chairman of Breitbart News.

In world news, thousands of Spaniards in Barcelona assembled along La Rambla in an act of defiance against terrorism less than 24 hours after a van rammed into crowds …

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Primecuts – This Week in the Journals

August 14, 2017
Primecuts – This Week in the Journals

By Jonathan Whitehouse, MD

Peer Reviewed

In New York last week, Mayor de Blasio announced a plan to tax wealthy New Yorkers in order to raise funds for our enfeebled subway system.  It was seen by many as a direct political clash with Governor Cuomo over funding for the Metropolitan Transportation Authority, at a time when the subways are plagued by delays and cancellations, and when both politicians are preparing for elections (1). Other well-documented problems include an “antiquated signal system, severe overcrowding, and trains …

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Can I Safely Use Anticoagulants in my Patient with a Brain Tumor?

August 3, 2017
Can I Safely Use Anticoagulants in my Patient with a Brain Tumor?

By Christopher Sonne, MD

Peer Reviewed

It is the last admission of your admitting night shift. You are called to assess a pleasant, oriented 65-year-old man with lung cancer and metastases to the bone, liver, and brain. You review his history along with his admission labs and imaging, and you quickly feel confident in your diagnosis of a lobar pneumonia. Relieved, tired, the sun peaking through the call window, you begin to put in his orders. Finally, your last task is to choose adequate venous …

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