PrimeCuts

ShortCuts-This Week in the Journals

October 2, 2007
ShortCuts-This Week in the Journals

Commentary by Danise Schiliro-Chuang MD, NYU Chief Resident

Let’s start on the theme of cardiovascular disease risk reduction, a topic making headlines this week. A September 28 New York Times article previews the release of new guidelines on perioperative care for patients undergoing noncardiac surgery. The guidelines, written by a panel of experts from the ACC and AHA, will recommend that patients undergo evaluation and treatment before noncardiac surgery only for active cardiac diseases such as severe angina, late-stage heart failure, significant arrhythmias and…

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ShortCuts-This Week in the Journals

September 23, 2007
ShortCuts-This Week in the Journals

Commentary by Cara Litvin MD, Executive Editor, Clinical Correlations

The sensation of déjà vu was likely very common this week. First, we experienced a flashback to 1994 when we saw OJ in handcuffs again…and then Hillary unveiled her new plan for universal health care. Her plan would require everyone to buy insurance, but emphasizes choices, including both the currently existing private options in addition to a public plan similar to Medicare. The plan also includes tax credits for families and small businesses to…

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ShortCuts-This Week in the Journals

September 17, 2007
ShortCuts-This Week in the Journals

Commentary by Henry Tran, MD

There continues to be accumulating evidence of the beneficial effects of statin therapy.  Coming on the heels of the SPARCL trial, which demonstrated that high-dose atorvastatin reduces the incidence of recurrent ischemic strokes in patients with recent TIA or stroke, is a randomized trial examining the effects of statin withdrawal.  Many patients with acute strokes have medications temporarily discontinued upon hospitalization, for instance due to dysphagia or apsiration risks.  Blanco et al. found that patients who continued statin…

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ShortCuts-This Week in the Journals

September 10, 2007
ShortCuts-This Week in the Journals

Commentary by Judith Brenner MD, Associate Program Director, NYU Internal Medicine Residency Program

Anemia is very common in ICU patients, but whether to treat this anemia and prevent the need for transfusions is currently unknown. Previous reports have actually suggested a decreased likelihood of survival associated with red cell transfusions. This week’s lead article in NEJM reports on a prospective, randomized placebo-controlled trial in which 1500 critically ill patients were treated with epoetin alfa vs placebo for up to 3 weeks. There was…

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Shortcuts-This Week in the Journals

September 5, 2007
Shortcuts-This Week in the Journals

Commentary by Michael Poles MD, Associate Editor Clinical Correlations

The latest estimates from the US Census Bureau suggest that the number of uninsured Americans has increased from 44.8 million in 2005 to roughly 47 million in 2006. This jump of 5 percent is the largest one-year increase in the number of uninsured since 2002. In that year, more than 18,000 American deaths were attributable to the lack of insurance and proper health care.

Physicians commonly look to systematic reviews to obtain current…

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ShortCuts-This Week in the Journals

August 27, 2007
ShortCuts-This Week in the Journals

Commentary by Josh Olstein MD, Associate Editor, Clinical Correlations

This week, the most popular health-care related story in the lay press was the news about Medicare’s plan to no longer cover the additional costs of treatment for many hospital-related complications such as catheter related infections and decubiti. The plan drew sweeping support from consumer advocacy groups who welcome any policy that would lead to increased patient safety and quickly caught the attention of hospital administrators and physicians. Administrators were unsurprisingly wary of the…

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Shortcuts-This Week in the Journals

August 20, 2007
Shortcuts-This Week in the Journals

Commentary By: Neil Shapiro, M.D. Editor-in-Chief Clinical Correlations

As summer winds down and the weather prematurely cools off, this weeks shortcuts finds us focusing on the genetics of coumadin treatment, the very controversial hpv vaccine, and the evils of direct to consumer advertising, and to keep us clean we conclude with a bit about antibacterial soaps and what else you can find at your local drugstore…

The front page of the wall street journal picked up an FDA medwatch advisory approving labeling…

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Shortcuts-This Week in the Journals

August 13, 2007
Shortcuts-This Week in the Journals

Commentary By Sean Cavanaugh, M.D. Associate Editor, Clinical Correlations

With the ever-increasing public concern about drug safety, and the profusion of wave-making research into clinical endpoints, occasional very public collisions are inevitable. And so opens this week’s Shortcuts…

Two recent seemingly opposing results were published in the past few weeks concerning the effects of statin therapy on patients with low LDL. Circulation featured a study looking at the safety and clinical outcomes associated with statin therapy in patients with very low LDL…

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ShortCuts-This Week in the Journals

August 6, 2007
ShortCuts-This Week in the Journals

Commentary by Cara Litvin MD, Executive Editor Clinical Correlations 

Avandia again made headlines this week when an FDA advisory committee voted to allow the drug to remain on the market despite new data that suggests it may increase the risk of ischemic heart disease. The committee overwhelmingly agreed that Avandia increases the risk of myocardial infarction in diabetic patients. However, in a remarkable vote of 22 to 1,  the committee nevertheless agreed that the drug should be kept on the market with new labeling.…

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ShortCuts-This Week in the Journals

July 30, 2007
ShortCuts-This Week in the Journals

Commentary by Henry Tran, MD

This week we will be highlighting a few articles examining risk factors for the development of obesity & the metabolic syndrome, a treatment for hypertrophic cardiomyopathy, and hospital rankings.

Many people think that soft drink consumption has been a major contributing factor to the global epidemic of obesity.  So is there an association between drinking soda and metabolic risk factors for heart diseases?  A study by Dhingra et al. published online by Circulation examined a cohort of…

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ShortCuts-This Week in the Journals

July 23, 2007
ShortCuts-This Week in the Journals

Commentary by Michael Poles MD, Associate Editor Clinical Correlations

Let’s start with a plea to counsel our patients, family members and friends to undergo colorectal cancer screening as it was reported yesterday that President Bush had 5 polyps removed from his colon.

Out of the newspapers and into the journals, we see that the Lancet is reporting that long-term antiretroviral therapy restores CD4 counts in HIV patients to normal. These antiretroviral-naïve patients, if they maintained undetectable viral loads below 50 copies/ml and…

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ShortCuts-This Week in the Journals

July 16, 2007
ShortCuts-This Week in the Journals

Commentary by Judith Brenner MD, Associate Program Director, NYU Internal Medicine Residency Program

This week we focus on breast cancer and the outcome associated with hereditary factors and controversies surrounding the seemingly uncontroversial annual physical exam

This week’s New England Journal of Medicine reports on clinical outcomes in patients with breast cancer who carry the BRCA1 and BRCA2 mutations.  The investigators set out to answer the question of whether breast cancers associated with BRCA1 and BRCA2 mutations are associated with a poorer outcome,…

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