PrimeCuts

ShortCuts-This Week in the Journals

August 27, 2007
ShortCuts-This Week in the Journals

Commentary by Josh Olstein MD, Associate Editor, Clinical Correlations

This week, the most popular health-care related story in the lay press was the news about Medicare’s plan to no longer cover the additional costs of treatment for many hospital-related complications such as catheter related infections and decubiti. The plan drew sweeping support from consumer advocacy groups who welcome any policy that would lead to increased patient safety and quickly caught the attention of hospital administrators and physicians. Administrators were unsurprisingly wary of the…

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Shortcuts-This Week in the Journals

August 20, 2007
Shortcuts-This Week in the Journals

Commentary By: Neil Shapiro, M.D. Editor-in-Chief Clinical Correlations

As summer winds down and the weather prematurely cools off, this weeks shortcuts finds us focusing on the genetics of coumadin treatment, the very controversial hpv vaccine, and the evils of direct to consumer advertising, and to keep us clean we conclude with a bit about antibacterial soaps and what else you can find at your local drugstore…

The front page of the wall street journal picked up an FDA medwatch advisory approving labeling…

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Shortcuts-This Week in the Journals

August 13, 2007
Shortcuts-This Week in the Journals

Commentary By Sean Cavanaugh, M.D. Associate Editor, Clinical Correlations

With the ever-increasing public concern about drug safety, and the profusion of wave-making research into clinical endpoints, occasional very public collisions are inevitable. And so opens this week’s Shortcuts…

Two recent seemingly opposing results were published in the past few weeks concerning the effects of statin therapy on patients with low LDL. Circulation featured a study looking at the safety and clinical outcomes associated with statin therapy in patients with very low LDL…

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ShortCuts-This Week in the Journals

August 6, 2007
ShortCuts-This Week in the Journals

Commentary by Cara Litvin MD, Executive Editor Clinical Correlations 

Avandia again made headlines this week when an FDA advisory committee voted to allow the drug to remain on the market despite new data that suggests it may increase the risk of ischemic heart disease. The committee overwhelmingly agreed that Avandia increases the risk of myocardial infarction in diabetic patients. However, in a remarkable vote of 22 to 1,  the committee nevertheless agreed that the drug should be kept on the market with new labeling.…

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ShortCuts-This Week in the Journals

July 30, 2007
ShortCuts-This Week in the Journals

Commentary by Henry Tran, MD

This week we will be highlighting a few articles examining risk factors for the development of obesity & the metabolic syndrome, a treatment for hypertrophic cardiomyopathy, and hospital rankings.

Many people think that soft drink consumption has been a major contributing factor to the global epidemic of obesity.  So is there an association between drinking soda and metabolic risk factors for heart diseases?  A study by Dhingra et al. published online by Circulation examined a cohort of…

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ShortCuts-This Week in the Journals

July 23, 2007
ShortCuts-This Week in the Journals

Commentary by Michael Poles MD, Associate Editor Clinical Correlations

Let’s start with a plea to counsel our patients, family members and friends to undergo colorectal cancer screening as it was reported yesterday that President Bush had 5 polyps removed from his colon.

Out of the newspapers and into the journals, we see that the Lancet is reporting that long-term antiretroviral therapy restores CD4 counts in HIV patients to normal. These antiretroviral-naïve patients, if they maintained undetectable viral loads below 50 copies/ml and…

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ShortCuts-This Week in the Journals

July 16, 2007
ShortCuts-This Week in the Journals

Commentary by Judith Brenner MD, Associate Program Director, NYU Internal Medicine Residency Program

This week we focus on breast cancer and the outcome associated with hereditary factors and controversies surrounding the seemingly uncontroversial annual physical exam

This week’s New England Journal of Medicine reports on clinical outcomes in patients with breast cancer who carry the BRCA1 and BRCA2 mutations.  The investigators set out to answer the question of whether breast cancers associated with BRCA1 and BRCA2 mutations are associated with a poorer outcome,…

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ShortCuts-This Week in the Journals

July 9, 2007
ShortCuts-This Week in the Journals

This week finds us talking about markers for chronic kidney disease (remember we’re no longer allowed to use terms such as renal insufficiency),  a bit of positive news about a popular alternative medicine, a new inflammatory marker for coronary artery disease, a genetic basis for atrial fibrillation and most importantly the value of an adequate intake of chocolate.

The 7/3 issue of the Annals of Internal Medicine furthers our knowledge of cystatin c as an eventual replacement for creatinine and gfr.  Cystatin c is a serum…

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Shortcuts-This Week in the Journals

July 2, 2007
Shortcuts-This Week in the Journals

Commentary By: Josh Olstein, M.D. Chief Resident Internal Medicine

This week, the NEJM released the results of a survey about needlestick injuries among surgical residents. The frequency of needlestick injuries were quite high, residents averaged 3.8 injuries across all years of training. By their fifth year of training 99% of residents had experienced at least one needlestick injury. Perhaps the most shocking statistics however were the frequency of unreported needlestick injuries, including those related to high-risk patients. When surveyed about their latest exposure,…

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ShortCuts-This Week in The Journals

June 25, 2007
ShortCuts-This Week in The Journals

Commentary By: Sean Cavanaugh MD, Associate Editor Clinical Correlations

Not much in the way of surprise, a lot of the articles in the press this past week focused on cardiovascular health.

In the Lancet, the results of the VALIDD trial (the acronyms are getting a bit ridiculous eh?) were published. Although it seems that valsartan was not more effective than other agents at improving diastolic dysfunction, it seems that lowering the blood pressure aggressively (using any agents) DID effectively improve diastolic functioning.…

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ShortCuts-This Week in The Journals

June 18, 2007
ShortCuts-This Week in The Journals

A study reported in this week’s issue of JAMA attempts to correlate preoperative hematocrit levels with postoperative outcomes in elderly veterans undergoing noncardiac surgery. Both 30-day postoperative mortality and cardiac event rates increased in patients with hematocrits either higher or lower than the normal range (39 to 53.9%). A 1.6% increase in mortality was associated with every percentage point positively or negatively deviating from the normal range. Although compelling, this study does not establish a causal relationship between hematocrit and postoperative complications, and…

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ShortCuts- This Week in the Journals

June 11, 2007
ShortCuts- This Week in the Journals

It has been a little while, but stem cells are back in the news. Congress has passed legislation to provide more money for stem cell research, but did not reach a veto-proof majority. Meanwhile, scientists at MIT have successfully transformed mice skin cells into the equivalent of embryonic stem cells. The presumption is that these cells, which are indistinguishable from embryonic stems cells can then be forced to develop into any tissue under the proper stimulation. While this approach might obviate the need to…

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