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A Bad Break for the Purple Pill…

January 8, 2007
A Bad Break for the Purple Pill…

Commentary By Josh Remick, PGY-2

In the December 27th 2006 issue of JAMA, Yang et al. reported the results of a nested case-control study of United Kingdom patients entitled “Long-term Proton Pump Inhibitor Therapy and Risk of Hip Fracture.” Using the General Practice Research Database (GPRD), a computerized medical record system used by several of the general medical practices in the UK, new hip fracture cases were found in patients at least 50 years old (n=13,556) and matched them with…

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Do Statins Get Along With Hepatitis C?

January 4, 2007
Do Statins Get Along With Hepatitis C?

A 53 year old male with chronic hepatitis C and type 2 diabetes is found to have a moderately elevated cholesterol.

1. Is it safe to start a statin?

2. Do statins have any effect on viral replication?

Comentary By Ed Bini, M.D. Associate Professor/Director Gastroenterology and Hepatology Research

The many benefits of statins far outweigh the risks associated with this class of medications. However, statins are known to have the potential to cause hepatotoxicity. The most common form of statin-induced hepatotoxicity is elevations in…

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How Frequently Should You Perform a Follow-Up Colonoscopy-A multiple choice quiz

January 2, 2007
How Frequently Should You Perform a Follow-Up Colonoscopy-A multiple choice quiz

Commentary By Michael Poles, M.D. Gastroenterologist, Assistant Professor of Medicine, Mircrobiology and Pathology.

Every once in a while I will be feeding this new blorganism (or is it bloganism?) with content from the world of gastroenterology. Today I would like to review an article of importance to both gastroenterologists and internists. There is likely no topic in gastroenterology more important than that of colorectal cancer screening. Colorectal cancer is the second most common cause of cancer death in the U.S., and it takes up…

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Diagnostic Dilemma #1-Faculty Response

November 8, 2006

Commentary By Michael Poles, M.D. Gastroenterologist, Assistant Professor of Medicine, Mircrobiology and Pathology.

Welcome blog readers to this inauguration of the NYU medicine blog. If the future cases are as interesting as this one, I am sure we will be having a lot of fun, and hopefully some learning.

OK, lets dive right in. We have the case of a young-ish guy who developed abnormal LFTs after starting a statin. Fortunately, the case is more interesting than just that…

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Diagnostic Dilemma #1

November 7, 2006
Diagnostic Dilemma #1

The first in our series of clinical cases with difficult management questions… Question: 59 y.o. male with pmh notable for hyperlipidemia. Pt had normal lft's, which increased mildly when he was put on a statin. His basic hepatitis screen including A, B and C were all negative, but an iron/tibc was 61% with a nl ferritin. A hemochromatosis gene analysis was sent which revealed a single mutation c282y-and he was designated a carrier. U/s showed a midly heterogeneous hepatic echotexture with no discrete lesions.
Questions
1:…

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