Clinical Pharmacy Corner-The Thiazides

May 17, 2007
Clinical Pharmacy Corner-The Thiazides

 We’d like to introduce you to Clinical Correlations’ newest feature-Clinical Pharmacy Corner. This will be a bimonthly pharmacy themed post which will tackle both basic and complicated pharmacy issues. We will review the mechanisms of actions of various classes of medications, a worthwhile refresher for those of us who may have forgotten what we learned in pharmacology 101 in medical school. We will also answer our reader’s pharmacy questions based on actual cases. As always please send your clinical questions and feedback to…

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Mystery Quiz #3-The Answer

May 15, 2007
Mystery Quiz #3-The Answer

Before you read the answer you should read the orginal post form last week

The Final Poll Results (26 votes): metastatic disease (26%) , mycobacterial disease (22%) ,fungal disease (22%), bronchiolitis obliterans with organizing pneumonia (boop) (13%), septic emboli (9%) ,vasculitis, e.g. wegener’s (4%), thromboembolic disease (4%), sarcoid (0%)

The patient had granulomatous inflammation on pathology with acid-fast organisms seen. The culture grew mycobacterium avium (MAC). After treatment with azithromycin, ethambutol and rifabutin for eighteen months, the follow-up imaging showed significant clearing…

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ShortCuts-The War on the Pharmaceutical Industry Edition

May 14, 2007
ShortCuts-The War on the Pharmaceutical Industry Edition

Welcome to our first theme issue of ShortCuts. This week, we decided to focus on the tribulations of the pharmaceutical industry, which recently seems to be plagued by new FDA advisories and NY Times exposés.

The first bad news for pharmaceutical companies occurred on May 2nd when the FDA expanded its black box warning on antidepressant medications, stating that the drugs may have the potential to increase suicidal symptoms in young adults between the ages of 18 and 24. The warning, previously targeting…

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Meeting Perspectives-Internal Medicine 2007 -The American College of Physicians

May 11, 2007
Meeting Perspectives-Internal Medicine 2007 -The American College of Physicians

By: Mitchell Charap, MD Senior Associate Program Director, NYU Internal Medicine Residency Program

The ACP’s annual session is a bit different from other major annual medical meetings. In general it is an excellent review of the prior year’s literature rather than a forum for breaking news and major announcements. Information that is vital to a practicing internist is reviewed in depth. What follows is a collection of what I found to be the most important and interesting clinical points that I took away…

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Clinical Pathology Conference 5/11/07

May 10, 2007
Clinical Pathology Conference 5/11/07

Welcome to the first posting of our NYU Department of Medicine’s Clinical Pathology Conference. Use the links below to review the case and the radiological findings. Our faculty and medical students will be attempting to diagnose this unknown case Friday in the 17 West Conference Room at Bellevue Hospital. Feel free to make your diagnosis by clicking the comment field below. For those who are unable to attend the live conference, we will reveal the answer next week.

CPC 5-11-07

CPC Radiology…

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The HPV vaccine: Recommended in the U.S., but required in Virginia

May 8, 2007
The HPV vaccine: Recommended in the U.S., but required in Virginia

Commentary By: Marshall Fordyce, PGY-3

Now that the dust has settled in Texas and Virginia, let’s clarify the role of the human papilloma virus (HPV) vaccine in our clinics. An excellent article in last week’s JAMA by its Editor-In-Chief, Dr. Catherine DeAngelis, and Lawrence Gostin, JD, highlights how the recent push for compulsory vaccination – a significant step beyond CDC recommendations – defied precedent and threatened public confidence in our national vaccine policy. Now, after the tussle of aggressive pharmaceutical lobbying and the…

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ShortCuts-This Week in the Journals

May 7, 2007
ShortCuts-This Week in the Journals

9p21. More than just three numbers and one letter, this stretch of DNA, which is present in 1 out of five Caucasians, results in a 64% increase in the risk of myocardial infarction. Two groups, performing genome-wide association studies, made this discovery, which would not have been possible before the work of the Human Genome Project. It should be noted that this mutation is not present in Africans and does not confer an increased risk in African Americans. This stretch of DNA is also…

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Mystery Quiz

May 3, 2007
Mystery Quiz

Posted By Robert Smith, MD Associate Professor of Medicine, Division Pulmonary and Critical Care Medicine

The patient is an 81 year old male with severe obstructive lung disease who was referred to the pulmonary service for an abnormal chest x-ray prior to femoral-popliteal bypass surgery.   The patient complained of chronic dyspnea on exertion but specifically denied hemoptysis, increased cough, fever or night sweats.   Initial cxr revealed the following:

A chest ct showed only a spiculated appearing mass in the left upper lobe…

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