Why is Syphilis Still Sensitive to Penicillin?

July 30, 2009
Why is Syphilis Still Sensitive to Penicillin?

Sam Rougas MD

Faculty Peer Reviewed

It seems that every week a new article in a major newspaper is reporting what most infectious disease physicians have been preaching for several years. Antibiotic resistance is rapidly spreading. Infections such as Methicillin Resistant Staphylococcal Aureus, Extremely Drug Resistant Tuberculosis, and Vancomycin Resistant Enterococcus have journeyed from the intensive care units to the locker rooms of the National Football League. That being said, some bacteria have strangely and until recently inexplicably behaved. Syphilis, a disease caused by the …

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The Asian Glow: A unique screening tool to evaluate for an elevated risk of esophageal cancer

July 29, 2009
The Asian Glow: A unique screening tool to evaluate for an elevated risk of esophageal cancer

Cindy Mui MD

Faculty Peer Reviewed

The alcohol flushing response is a physiologic response to ingestion of alcohol and is characterized by facial flushing, nausea, tachycardia, and hypotension, felt to be due to an inherited deficiency in the enzyme aldehyde dehydrogenase 2 (ALDH2). It is experienced by one third of East Asians and is more commonly known as the “Asian glow” or the “Asian flush”(1). Although the alcohol flushing response is generally seen as cosmetic and even embarrassing on a night out, there is evidence …

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PrimeCuts- This Week in the Journals

July 27, 2009
PrimeCuts- This Week in the Journals

Onyeka Okonkwo MD

Faculty peer reviewed

Alzheimer’s disease (AD) is the most common cause of dementia affecting over 4.5 million Americans, with cases in the US projected to triple over the next 40 years in the absence of advancements in therapy. With the aging of the American population, the disease has become an increasingly significant source of healthcare spending, with over 80 billion dollars dedicated annually to the care of patients with Alzheimer’s. Consequently, a number of research studies have been initiated to investigate …

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Practicing Medicine in Rural America

July 24, 2009
Practicing Medicine in Rural America

 

Erin Ducharme MD

This entry is the final in a three part series where I share highlights from my conversation with my home-town physician from rural southern Iowa. Here I discuss the medical conditions which affect this 4500 population town. I also briefly touch on maintaining privacy in a place where “Everybody knows your name (and your business)” and the incorporation of an electronic medical record system.  Please also see Part I and Part II.

Running Water and Computers too

The bread and butter diseases-congestive …

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Mystery Quiz- The Answer

July 23, 2009
Mystery Quiz- The Answer

Vivian Hayashi MD and Robert Smith MD, Mystery Quiz Section Editors

The answer to the mystery quiz is bland alveolar hemorrhage. The CXR (image 1) shows cardiomegaly with mild increase in opacification of the right middle and right lower lobes. The CT images show areas of multifocal ground glass opacification, that is, the underlying interstitium is visible through the opacification, and the variably sized opacities are widely distributed throughout the lungs (images 2, 3, and 4). Image 4 shows prominent interstitium through the ground glass. …

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Much Ado about Comparative Effectiveness

July 22, 2009
Much Ado about Comparative Effectiveness

Minal Kale MD
Nirav R. Shah MD, MPH

In the last few months, academic research communities have been all aflutter with the unprecedented sums of money that are up for grabs, as supported by the American Recovery and Reinvestment Act of 2009. The federal stimulus package promises $10.4 billion administered through the National Institutes of Health (NIH), 80% of which is devoted specifically to scientific research. The frenzy in applying for these monies belies the high level of organization that will go into submitting funding …

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PrimeCuts: This Week in the Journals

July 20, 2009
PrimeCuts: This Week in the Journals

Farshid Yazdi MD

Faculty Peer Reviewed

In America, we are quickly coming upon a moment in history that will likely affect us for decades to come. A recent article in the New York Times describes the upcoming health care bill as one that will transform our health care system. President Obama has vowed to have these bills passed before the summer sessions end, but some in Congress are apprehensive about releasing such a major bill so quickly. With 45 million Americans lacking health care coverage, …

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Mystery Quiz

July 18, 2009
Mystery Quiz

Vivian Hayashi MD and Robert Smith MD, Mystery Quiz Section Editors

The patient is a 74 year old man complaining of hemoptysis for four days. The patient has a history of hypertension, but had not been followed medically for many years until two weeks earlier when he presented with leg swelling, breathlessness, and atrial flutter. He was admitted, diuresed, begun on antihypertensive medications including hydralazine, aspirin, and anti-coagulated with enoxaparin and warfarin. After discharge, the patient felt well for a few days before the onset …

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