Gamechanger? Can Pioglitazone Reduce Cardiovascular Events After a Stroke? An Analysis of the IRIS Trial

January 19, 2017
Gamechanger?  Can Pioglitazone Reduce Cardiovascular Events After a Stroke?  An Analysis of the IRIS Trial

By Johanna Hase, MD

Peer Reviewed

Welcome to Gamechangers, a series that takes a critical look at the latest in medical literature to answer one important question: would the results of this article change my practice? Featuring thorough evidence-based review as well as expert commentary, our aim is for this series to help you decide if the results of a given study are, in fact, a gamechanger

A 64 year old woman with pre-diabetes, hyperlipidemia, and hypertension on aspirin, losartan and simvastatin, recently was diagnosed …

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Primecuts – This Week In The Journals

January 17, 2017
Primecuts – This Week In The Journals

By Scott Butler, MD 

Peer Reviewed

A presidential goodbye. A contentious press conference.  A salacious dossier from a British spy.  It’s been quite a week.

As Republican legislators transition from symbolically voting to repeal Obamacare (over 50 times since its inception) to making its dissolution a reality, it becomes increasingly clear that “replace” is the much more challenging half of the promise to “repeal and replace” the law. Theodore Roosevelt backed a plan for universal coverage when he sought an elusive third term in 1912.  …

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Myths and Realities: Is My Cirrhotic Patient Auto-anticoagulated?

January 12, 2017
Myths and Realities: Is My Cirrhotic Patient Auto-anticoagulated?

By B. Corbett Walsh, MD

Peer Reviewed

Case: A 65 year-old man with cirrhosis is admitted to the ICU for severe pneumonia. His hepatic dysfunction is chronically severe, as indicated by a MELD score of 31, and he has a stable thrombocytopenia of 110,000 platelets/ml. Should this patient be on DVT prophylaxis?

MYTH: Patients with severe hepatic dysfunction resulting in a significantly elevated INR are auto-anticoagulated and protected against venous thromboembolic events.

The liver is responsible for a plethora of processes: metabolic (carbohydrate and lipid …

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Primecuts – This Week In The Journals

January 9, 2017
Primecuts – This Week In The Journals

By: Nancyanne Schmidt, MD

Peer Reviewed

This week, the intelligence report commissioned by President Obama on suspected hacking during the recent presidential election revealed that Russian President Vladimir Putin ordered an influence campaign aimed at undermining The Democratic National Committee and Hillary Clinton’s campaign, in particular. The report, which compiled the collective assessments of the C.I.A., National Security Agency and F.B.I., stopped short of implicating Russia in the outcome of the recent presidential election in which President-elect Donald Trump defeated Hillary Clinton in a …

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Primecuts – This Week In The Journals

January 4, 2017
Primecuts – This Week In The Journals

By Derek Moriyama, MD

Peer Reviewed 

It is official. The members of the electoral college have cast their votes and Donald Trump will be the next President of the United States. As he continues to use twitter as a platform to inform the world of his beliefs, including a reference to the direction of our nuclear program , we are all left guessing how his Presidency will affect the future of our country and the world.

Aside from U.S. political news, there have been shocking …

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Primecuts-This Week in the Journals

December 19, 2016
Primecuts-This Week in the Journals

By B. Corbett Walsh, MD

Peer Reviewed

As many of us reflect on the festivities that occurred during the Department of Medicine Holiday Party this past weekend, all can agree that winter is not only coming, but that it has arrived. Earlier this week those inside New York University’s Langone Medical Center Tisch Hospital may have thought the excessive heating was premature, only to realize that a fire had broken out on 7th floor of the currently-under-construction Kimmel Pavilion. No injuries were reported, and the …

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Primecuts – This Week In The Journals

December 13, 2016
Primecuts – This Week In The Journals

By Shriram Alapaty, MD

Peer Reviewed

This week, America’s president-elect Donald Trump continued to defy expectations by selecting Mr. Scott Pruitt, a close ally of the fossil fuel industry, to head the Environmental Protection Agency. In stark contrast, Google has targeted 2017 as the date by which to completely run on renewable energy. The environment has been a subject of global attention, with Paris opting to make all public transport free in the face of the worst air pollution in 10 years. While America continues …

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Primecuts – This Week In The Journals

December 8, 2016
Primecuts – This Week In The Journals

By Robert Freilich, MD

Peer Reviewed

Levels of smoking have dropped to record lows in the United states. Per a NY Times article1, the CDC reports that smoking levels are down in Americans from 21% in 2005 to 15% in 2015. This represents a reduction of almost 9 million Americans who are smoking. Encouragingly, smoking declined the greatest among the youngest age groups. Fifteen percent is the lowest level since the US began recording levels of smoking 50 years ago. Moving from population changes leading …

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