Primecuts – This Week in the Journals

September 6, 2017
Primecuts – This Week in the Journals

By Rushad Dordi, MD

Peer Reviewed

This week’s Primecuts details four examples of novel methodologies for treating common diseases. We begin first with a study repurposing an anti-inflammatory therapeutic for the treatment of atherosclerosis, and move onto a new targeted gene therapy for malignant mesothelioma. Finally, we touch on using probiotics to modify peanut allergies, based on a novel understanding of immunogenicity, and using the immune system to assist regulation in type 1-diabetes. Together, these studies show the power of creative thinking in the scientific …

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Primecuts – This Week in the Journals

August 29, 2017
Primecuts – This Week in the Journals

By Scarlett Murphy, MD

Peer Reviewed

American attention shifted away from challenging national conversations in the wake of Charlottesville towards the sky this past Monday, when a total solar eclipse traversed the entire US mainland for the first time since 1918 (1).  Although we missed out on the breath-taking experience of totality, New Yorkers still enjoyed a 72% partial eclipse (2).

President Trump held a special rally in Arizona, where he criticized the media for propagating his comments about Charlottesville that seemed to some to …

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Health Care: Do Celebrities Know Best?

August 24, 2017
Health Care: Do Celebrities Know Best?

Please enjoy this post from the archives dated August 25, 2013

By Emma Gorynski

Faculty Peer Reviewed

The power that celebrities have over Americans is undeniable. We look to them for guidance on what to listen to, what to wear, and even what to name our children. Celebrities even affect the decisions we make about our own health care. With the increasing popularity of direct-to-consumer advertising, celebrities are promoting pharmaceuticals and other health-related products.

Is there a role for celebrities in health advocacy? On one …

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Should Beta Blockers be Used in Heart Failure with Preserved Ejection Fraction?

August 23, 2017
Should Beta Blockers be Used in Heart Failure with Preserved Ejection Fraction?

By Lauren Christene Strazzulla

Peer Reviewed

The lifetime risk for developing heart failure from age 55 on is 33% for men and 28.5% for women, and as the population ages, there is an increasing prevalence of this disease along with its associated health care costs . Heart failure is divisible into 2 distinct entities: those with left ventricular systolic dysfunction and those with cardiovascular compromise that does not decrease LV ejection fraction, which is termed heart failure with persevered ejection fraction (HFpEF) . While …

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Primecuts – This Week in the Journals

August 21, 2017
Primecuts – This Week in the Journals

By Andrew Armanious, MD

Peer Reviewed

This past week, President Trump decided to part ways with White House Chief Strategist Steve Bannon (1). Bannon was a controversial and blunt-spoken political figure who influenced President Trump on many of his contentious campaign decisions. Bannon will be returning to his prior position of executive chairman of Breitbart News.

In world news, thousands of Spaniards in Barcelona assembled along La Rambla in an act of defiance against terrorism less than 24 hours after a van rammed into crowds …

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When Doctors Get Personal

August 18, 2017
When Doctors Get Personal

By Leland Soiefer

Peer Reviewed

Mrs. S sat up straight and made excellent eye contact. Her tone was pleasant. She wore a colorful yellow shirt and dark green pants, and was accompanied by her husband; her gilded rings and earrings added flair to her outfit. Her neutral expression, however, stood out to me. She had seen a doctor several weeks ago regarding her first vaginal bleeding since menopause, and a uterine biopsy showing a precancerous lesion was subsequently performed. Surely by this point she had …

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From the Archives: Are We Too Hesitant to Anticoagulate Elderly Patients with Atrial Fibrillation? A Risk-Benefit Analysis

August 17, 2017
From the Archives: Are We Too Hesitant to Anticoagulate Elderly Patients with Atrial Fibrillation? A Risk-Benefit Analysis

Please enjoy this post from the archives dated June 28, 2013

By Sunny N. Shah, MD

Faculty Peer Reviewed

Background:

Atrial fibrillation (AF) is the most common cardiac arrhythmia and its prevalence increases with age. In fact, the lifetime incidence of AF is approximately 25% in individuals by age 80, with the incidence nearly doubling with each decade of life after age 50. (1) Multiple randomized controlled trials have shown that oral antithrombotic therapy with warfarin or aspirin decreases the risk of ischemic stroke in …

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Primecuts – This Week in the Journals

August 14, 2017
Primecuts – This Week in the Journals

By Jonathan Whitehouse, MD

Peer Reviewed

In New York last week, Mayor de Blasio announced a plan to tax wealthy New Yorkers in order to raise funds for our enfeebled subway system.  It was seen by many as a direct political clash with Governor Cuomo over funding for the Metropolitan Transportation Authority, at a time when the subways are plagued by delays and cancellations, and when both politicians are preparing for elections (1). Other well-documented problems include an “antiquated signal system, severe overcrowding, and trains …

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