ShortCuts- This Week in the Journals

June 11, 2007
ShortCuts- This Week in the Journals

It has been a little while, but stem cells are back in the news. Congress has passed legislation to provide more money for stem cell research, but did not reach a veto-proof majority. Meanwhile, scientists at MIT have successfully transformed mice skin cells into the equivalent of embryonic stem cells. The presumption is that these cells, which are indistinguishable from embryonic stems cells can then be forced to develop into any tissue under the proper stimulation. While this approach might obviate the need to…

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Clinical Pathology Conference 6/8/07

June 7, 2007
Clinical Pathology Conference 6/8/07

Welcome to the monthly posting of our NYU Department of Medicine’s Clinical Pathology Conference. Use the links below to review the case and the radiological findings. Our faculty and medical students will be attempting to diagnose this unknown case Friday in the 17 West Conference Room at Bellevue Hospital. Feel free to make your diagnosis by clicking the comment field below. For those who are unable to attend the live conference, we will reveal the answer next week.

CPC 6/8/07

CPC Radiology 6/8/07…

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Can you switch a patient from insulin to oral agents?

June 6, 2007
Can you switch a patient from insulin to oral agents?

  A 48 year old male is diagnosed with type 2 Diabetes Mellitus after presenting to the emergency room with symptoms of hyperglycemia. He was immediately started on insulin and has been very compliant with his regimen. His initial Hemoglobin A1C at the time of diagnosis was 15.  However, over the past few months, due to hypoglycemia, his insulin dosage has been titrated down. He is currently on low doses of NPH and aspart, with an A1C of 6.6. Would it be possible to

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Meeting Perspectives: 2007 American Thoracic Society International Conference

June 5, 2007
Meeting Perspectives: 2007 American Thoracic Society International Conference

Commentary by Doreen Addrizzo-Harris MD, Associate Professor, Division of Pulmonary and Critical Care Medicine

The 2007 American Thoracic Society (ATS) meeting took place between May18-23 in San Francisco, California at the Moscone Conference center.  There were more than 400 sessions, 800 speakers and 5,500 original research abstracts.  The meeting is concentrated in the areas of pulmonary, critical care and sleep medicine.

The NYU Division of Pulmonary and Critical Care medicine, under the direction of Dr. William N. Rom, presented more than 30…

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ShortCuts-This Week in the Journals

June 4, 2007
ShortCuts-This Week in the Journals

Much of the week in the media was spent discussing XDR TB. Andrew Speaker, a man on his way to his wedding in Santorini Greece (the picture of his wedding is to the right) managed to evade US security multiple times. The story is convoluted with many people telling different versions. It appears that he has smear negative, culture positive XDR-TB. His now father-in-law is a TB researcher, who insists that his new son-in-law did not catch it from his lab. Most importantly, when officials…

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Meeting Perspectives-Internal Medicine 2007-The American College of Physicians,Part 2 (continued)

June 1, 2007
Meeting Perspectives-Internal Medicine 2007-The American College of Physicians,Part 2 (continued)

Commentary by Mitchell Charap, MD Senior Associate Program Director, NYU Internal Medicine Residency Program

I now return (See previous post) to my discussion of the STAR *D report (Am J Psychiatry. 2006;106) which is a very important study of antidepressant therapy conducted by NIMH. 4000 patients at 41 sites (18 general medical settings). There was no placebo control. Those patients who failed monotherapy with citalopram (up to 60 mg) were offered two options: switching to another therapy or…

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Recent Developments in the Treatment of Renal Cell Carcinoma

May 31, 2007
Recent Developments in the Treatment of Renal Cell Carcinoma

Commentary by Michael Seidman MD, Chief Oncology Fellow

New treatment options for both early and advanced Renal Cell Cancer have recently been published. Traditionally, treatment for early stage disease was partial or radical nephrectomy. In the metastatic setting, treatment options were limited to toxic cytokine therapy with IFN or IL-2.

Some recent literature has suggested that small, incidentally found renal tumors can safely be watched without the need for invasive surgery. Remzi et al retrospectively reviewed 287 tumor bearing kidneys 4cm or…

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New Guidelines on the Management of Intracerebral Hemorrhage

May 30, 2007
New Guidelines on the Management of Intracerebral Hemorrhage

Commentary by Dr. Daniel Labovitz, Director of the NYU Stroke Center

After an 8-year hiatus, the American Heart Association/American Stroke Association has at last published a fresh set of guidelines on the management of acute spontaneous intracerebral hemorrhage (ICH) . ICH represents between 10 and 20% of all first strokes, depending on the population, but carries a mortality rate of 35% to 50%, with hemorrhage volume, hemorrhage location, intraventricular extension and age all contributing independently to the risk of death.…

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