Not So Rosi…

May 24, 2007
Not So Rosi…

Commentary by Seagram Villagomez MD, Chief Resident

Since its approval in 1999, nearly 1 million Americans have used the thiazolidinedione (TZD) rosiglitazone (Avandia – GlaxoSmithKline) for the treatment of Type 2 Diabetes.  However, in a drug class which seems plagued by concerns, the safety profile associated with rosiglitazone has been brought to question. Previously, troglitazone (Rezulin) was pulled off the market secondary to hepatoxicity, while muraglitazar was not approved by the FDA given adverse cardiovascular events during early clinical trials.  In a…

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ShortCuts-This Week in the Journals

May 21, 2007
ShortCuts-This Week in the Journals

This week’s review is a potpourri of interesting if not groundbreaking articles.

The pharmaceutical industry certainly got off easier this week (see last week’s shortcuts) and the New York Times focused instead on the “industrialization” of the art of medicine. A hospital group in central Pennsylvania is offering insurers and patients bypass surgery for a flat fee with a 90 day guarantee. They’ve put 40 measures in place to make sure patients receive evidenced based care. If the any of the 40 measure…

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Clinical Pathology Conference 5/11/07-The Answer

May 18, 2007

Please review the posting of last week’s  CPC Case here.

When you’re ready you can download the CPC Answer here.

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Clinical Pharmacy Corner-The Thiazides

May 17, 2007
Clinical Pharmacy Corner-The Thiazides

 We’d like to introduce you to Clinical Correlations’ newest feature-Clinical Pharmacy Corner. This will be a bimonthly pharmacy themed post which will tackle both basic and complicated pharmacy issues. We will review the mechanisms of actions of various classes of medications, a worthwhile refresher for those of us who may have forgotten what we learned in pharmacology 101 in medical school. We will also answer our reader’s pharmacy questions based on actual cases. As always please send your clinical questions and feedback to…

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Mystery Quiz #3-The Answer

May 15, 2007
Mystery Quiz #3-The Answer

Before you read the answer you should read the orginal post form last week

The Final Poll Results (26 votes): metastatic disease (26%) , mycobacterial disease (22%) ,fungal disease (22%), bronchiolitis obliterans with organizing pneumonia (boop) (13%), septic emboli (9%) ,vasculitis, e.g. wegener’s (4%), thromboembolic disease (4%), sarcoid (0%)

The patient had granulomatous inflammation on pathology with acid-fast organisms seen. The culture grew mycobacterium avium (MAC). After treatment with azithromycin, ethambutol and rifabutin for eighteen months, the follow-up imaging showed significant clearing…

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ShortCuts-The War on the Pharmaceutical Industry Edition

May 14, 2007
ShortCuts-The War on the Pharmaceutical Industry Edition

Welcome to our first theme issue of ShortCuts. This week, we decided to focus on the tribulations of the pharmaceutical industry, which recently seems to be plagued by new FDA advisories and NY Times exposés.

The first bad news for pharmaceutical companies occurred on May 2nd when the FDA expanded its black box warning on antidepressant medications, stating that the drugs may have the potential to increase suicidal symptoms in young adults between the ages of 18 and 24. The warning, previously targeting…

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Meeting Perspectives-Internal Medicine 2007 -The American College of Physicians

May 11, 2007
Meeting Perspectives-Internal Medicine 2007 -The American College of Physicians

By: Mitchell Charap, MD Senior Associate Program Director, NYU Internal Medicine Residency Program

The ACP’s annual session is a bit different from other major annual medical meetings. In general it is an excellent review of the prior year’s literature rather than a forum for breaking news and major announcements. Information that is vital to a practicing internist is reviewed in depth. What follows is a collection of what I found to be the most important and interesting clinical points that I took away…

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Clinical Pathology Conference 5/11/07

May 10, 2007
Clinical Pathology Conference 5/11/07

Welcome to the first posting of our NYU Department of Medicine’s Clinical Pathology Conference. Use the links below to review the case and the radiological findings. Our faculty and medical students will be attempting to diagnose this unknown case Friday in the 17 West Conference Room at Bellevue Hospital. Feel free to make your diagnosis by clicking the comment field below. For those who are unable to attend the live conference, we will reveal the answer next week.

CPC 5-11-07

CPC Radiology…

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