Is It Time to Reconsider Who Should Get Metformin?

December 11, 2015
Is It Time to Reconsider Who Should Get Metformin?

By Lauren Strazzulla

Current FDA guidelines for the use of metformin stipulate that it not be prescribed to those with an elevated creatinine (at or above 1.5 mg/dL for men and 1.4 mg/dL for women). It is also contraindicated in patients with heart failure requiring pharmacologic treatment, and people over age 80, unless their creatinine demonstrates that renal function is not reduced. These guidelines are in place to prevent lactic acidosis, an understandably feared complication of metformin. However, metformin is, by consensus, the initial drug …

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Primecuts – This Week In The Journals

December 8, 2015
Primecuts – This Week In The Journals

Jiwoon Chang, MD

Peer Reviewed 

This past week we witnessed another senseless mass shooting in San Bernardino, California that killed 14 people. The FBI is investigating this act of violence as a terror attack and the assailants’ link to ISIS . On average shootings that kill or injure more than 3 people occurred once or more per day in the United States this year . In other news US health spending increased by 5.3% last year to $3 trillion, likely due to expanded insurance coverage …

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Primecuts-This Week in the Journals

November 23, 2015
Primecuts-This Week in the Journals

By Noam Broder, MD

This week in Primecuts we take a moment to honor the victims of the recent terror attacks in Paris and the emergency response teams who cared for the wounded. According to the Wall Street Journal, Paris’s hospital authority triggered its “Plan Blanc” at about 10:30 pm local time Friday, effectively calling medical personnel to work, getting ambulances on the road, and beds readied ahead of the expected patients. American hospitals have emergency plans similar to “Plan Blanc” with strategies for dealing …

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Primecuts-This Week in the Journals

November 17, 2015
Primecuts-This Week in the Journals

By Amy Shen Tang, MD

Friday, November 13th unfortunately proved to be more than an unlucky day for Parisians. What initially sounded like firecrackers outside a soccer match at the Stade de France, with President Francois Hollande in attendance, was quickly realized to be the first suicide bomber detonating explosives. Soon after, gunfire and suicide bombs erupted at Bataclan Music Hall and four other sites simultaneously, culminating in well over 100 deaths and more than 350 wounded. President Hollande declared a state of emergency as …

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Are We Overusing Proton Pump Inhibitors?

November 13, 2015
Are We Overusing Proton Pump Inhibitors?

By Shimwoo Lee
Peer Reviewed
Case: A 31-year-old man with poorly controlled type 2 diabetes was hospitalized for community-acquired pneumonia. His home medications included esomeprazole. When asked why he was receiving this medication, the patient said it was first started during his prior hospitalization for “ulcer prevention” eight months ago and that he had continued to take it since. He denied any history of upper gastrointestinal symptoms. Esomeprazole was tapered off during this admission. When being discharged after successful treatment of his pneumonia, he was …

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Primecuts-This Week in the Journals

November 10, 2015
Primecuts-This Week in the Journals

By: Loren Franco, MD

Russia has suspended all flights to Egypt amidst mounting reports and evidence that a terrorist bomb took down the Metrojet flight to St. Petersburg. Last week on October 31st, a Metrojet plane carrying 224 individuals exploded soon after taking off in a resort town in Egypt on its way to St. Petersburg, killing everyone on board. Soon after the news hit, ISIS affiliates began to take credit for the crash but never described how it was done, prompting authorities to question …

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Primecuts-This Week in the Journals

November 3, 2015
Primecuts-This Week in the Journals

By Stephanie Wu, MD

Peer Reviewed

This past weekend, we cheered for the 50,000 people who ran the NYC marathon. Jonathan Mendes, at 94 years old, tackled this marathon for his 14th time . In the midst of this momentous and triumphant occasion, we witnessed the tragic loss of 224 people on board a plane that crashed in Egypt. Earlier in the week, China repealed its one-child policy that had been in place since 1979. With plenty of Halloween candy in our stomachs and an …

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Supporting Evidence

October 30, 2015
Supporting Evidence

By: Amy Ou

During a weekend off at my parents’ home, the subject of this chronic cough that I had developed for the entirety of the winter season came up. My mother, noticeably more concerned about it than I, asked: “Did you get a flu shot? Did you get your cough after you got your flu shot? You know this happened when you were little, right? I just don’t know about those flu shots, I think they have some bad side effects. Your dad and …

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