Introducing the CORE IM Podcasts: 5 Pearls & Mind the Gap

October 13, 2017

By Shreya P. Trivedi, MD, Martin Fried, MD and Neil Shapiro, MD

Stay tuned as Clinical Correlations will be partnering with CORE IM to bring our audience podcasts!  CORE IM is a consortium of educators aligned to create internal medicine-specific portable learning tools in the form of podcasts, corresponding show notes and illustrations.  Our goal is to help today’s busy clinician synthesize and consolidate important teaching points. The podcast will deliver high-yield digestible content on various clinically relevant internal medicine topics that can be easily incorporated into demanding schedules.

Read more »

Spotlight: Subacute Endocarditis: The Great Masquerader

October 11, 2017
Spotlight: Subacute Endocarditis: The Great Masquerader

By  Helen Ma, MD

Peer Reviewed

Our new Spotlight series uses case vignettes to explore diagnosis, pathophysiology, and management of a wide variety of diseases seen in the outpatient and inpatient settings.  Articles in the Spotlight section contain clinical pearls that will be highlighted in the case discussion.  While the occasional zebra may appear, the goal of the series is to provide clinically relevant information, and each case has been selected specifically for the relevance of its learning points rather than its rarity. 

Learning objectives

Read more »

Primecuts – This Week in the Journals

October 9, 2017
Primecuts – This Week in the Journals

By Joanne Bruno, MD/PhD

Peer Reviewed 

There’s finally starting to be a bit more of a chill in the air, which can only mean one thing – pie season is finally here! While this time of year is rife with celebration and gluttony, it is also a time to give back to those in need. This is especially relevant this year given that Puerto Rico is still reeling from the devastation left by Hurricane Maria and Las Vegas just experienced one of the worst mass …

Read more »

Reducing Readmission in Sickle Cell Disease: The Role of the Patient-Centered Medical Home

October 6, 2017
Reducing Readmission in Sickle Cell Disease: The Role of the Patient-Centered Medical Home

By Leonard Naymagon, MD

Peer Reviewed

Vaso-occlusive crisis (VOC), or pain crisis, is the most common clinical manifestation of sickle cell disease (SCD) and is responsible for the majority of emergency department (ED) visits and inpatient hospitalizations among sickle cell patients . A retrospective analysis of over 100,000 in-hospital encounters for VOC in 2005 and 2006 demonstrated 30-day and 14-day rehospitalization rates of 33.4% and 22.1% respectively . These findings were most pronounced among 18- to 30-year-olds, with 41.1% rehospitalized within 30 days and 28.4% …

Read more »

From The Archives -The DLO: Does FFP Correct INR?

October 5, 2017
From The Archives -The DLO: Does FFP Correct INR?

Please enjoy this post from the archives date September 20, 2013

By Nicole A Lamparello, MD

Faculty Peer Reviewed

Page from the hematology laboratory: critical lab value; INR 1.9. Liver biopsy scheduled for tomorrow. What is a knowledgeable physician practicing evidence-based medicine to do?

Fresh frozen plasma (FFP) is the liquid, acellular component of blood. FFP contains water, electrolytes, and the majority of the coagulation proteins . It is frequently transfused to patients with an elevated prothrombin time (PT), a measure of the activity of …

Read more »

Alzheimer’s Disease: State of Diagnosis

October 4, 2017
Alzheimer’s Disease: State of Diagnosis

By Karen McCloskey, MD

Peer Reviewed

In May 2012, The U.S. Department of Health and Human Services unveiled the “National Plan to Address Alzheimer’s Disease,” in response to legislation signed by President Obama in January, 2011 establishing the National Alzheimer’s Project Act.  The overarching goal of the Plan is to “prevent or effectively treat Alzheimer’s Disease by 2025.”   We now have an estimated 5.5 million people who are living with this illness and these numbers are only expected to grow with the aging population̶ the …

Read more »

Primecuts – This Week in the Journals

October 2, 2017
Primecuts – This Week in the Journals

By Kumar Vasudevan, MD

Peer Reviewed

With October beginning and the weather starting to change, the season for apple picking, Pumpkin Spice Lattes, and football also commences. However, with all the joys of fall, we also begin flu season and prepare for all the complications that it brings.  With this in mind, we turn to the medical literature which searches for novel treatments for this deadly illness.

Oseltamivir, Amantadine and Ribavirin Combination Antiviral Therapy versus Oseltamivir Monotherapy for the Treatment of Influenza

The flu is …

Read more »

Life and Limb: Battlefield Medicine from WWII to Today

September 29, 2017
Life and Limb:  Battlefield Medicine from WWII to Today

By Eric Jeffrey Nisenbaum, MD

Peer Reviewed

Mr. O is a 93-year-old man with a past medical history notable for severe Alzheimer’s dementia and amputation of the left upper extremity secondary to wounds received in WWII who was brought in from his nursing home with fever and dyspnea for two days.  His physical exam was notable for inspiratory crackles at the right lung base.  His CBC was notable for an elevated WBC with left-shift and a chest x-ray revealing a right lower lobe infiltrate. He …

Read more »