Systems

Tamiflu Patients Need Monitoring

November 14, 2006
Tamiflu Patients Need Monitoring

Over 100 cases have been reported to the FDA involving the use of Tamiflu and the development of hallucinations, delerium and other unusual behavior mainly in Japanese children.  From the Chicago Tribune article "Health officials have been sensitive about taking any action that might dissuade people from taking Tamiflu, since the drug could play an important role in an outbreak of bird flu."

Read more about it in the Chicago Tribune and FDA websites…here are the links:

FDA announcement

Chicago Tribune Story

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Improving Stroke Recovery-The EXCITE Trial

November 9, 2006
Improving Stroke Recovery-The EXCITE Trial

The EXCITE trial was the lead article in last week’s JAMA. It looks at a 2 week program of contstraint induced movement therapy vs. usual care in patients suffering a cva within the previous 3-9 months. Pt’s in the treatment arm wore a restraining mitt on the less-affected hand and engaged in tasks/behaviors with the hemiplegic hand. This group was compared to a control group with usual care. Measures of performance time and motor function ability all showed clinically relevant improvements that persisted out…

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Diagnostic Dilemma #1-Faculty Response

November 8, 2006

Commentary By Michael Poles, M.D. Gastroenterologist, Assistant Professor of Medicine, Mircrobiology and Pathology.

Welcome blog readers to this inauguration of the NYU medicine blog. If the future cases are as interesting as this one, I am sure we will be having a lot of fun, and hopefully some learning.

OK, lets dive right in. We have the case of a young-ish guy who developed abnormal LFTs after starting a statin. Fortunately, the case is more interesting than just that…

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Diagnostic Dilemma #1

November 7, 2006
Diagnostic Dilemma #1

The first in our series of clinical cases with difficult management questions… Question: 59 y.o. male with pmh notable for hyperlipidemia. Pt had normal lft's, which increased mildly when he was put on a statin. His basic hepatitis screen including A, B and C were all negative, but an iron/tibc was 61% with a nl ferritin. A hemochromatosis gene analysis was sent which revealed a single mutation c282y-and he was designated a carrier. U/s showed a midly heterogeneous hepatic echotexture with no discrete lesions.
Questions
1:…

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Statins and CHF

November 3, 2006
Statins and CHF

This week’s JAMA has an enormous study that looks at chf patients and the use of statins. Data from ~25,000 patients with chf were analyzed for use of statin in the 120 days prior to the initial chf diagnosis. Mortality risk was significantly lower for statin users than nonusers (hazard ratio 0.79), as was hospitalization (hr 0.80). Findings did not change by etiology of chf or whether the patient had cad. The press is taking this study to mean all patients with chf should be

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Headlines: Salmonella Outbreak

November 2, 2006

The CDC and the FDA announced yesterday that they are investigating an outbreak of Salmonella typhimurium illness that has affected at least 171 people in 19 states. Symptoms include fever and nonbloody diarrhea. The outbreak seems to be subsiding and they are still unclear as to the source suspecting tomatoes or letuce. No deaths as of yet, 11 patients hosptialized. Cases have been seen in Arkansas, Connecticut, Georgia, Indiana, Kentucky, Maine, Massachusetts, Michigan, Minnesota, North Carolina, New Hampshire, Ohio, Pennsylvania, Rhode Island, Tennessee, Virginia, Vermont,

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Syncope W/U

November 1, 2006
Syncope W/U

Don’t forget to ask your patients whether they recently attended a screening of Saw III when they are admitted with syncope…

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Listen Now to Thyroid Disorders

October 31, 2006

Check out this example of the Cleveland Clinic podcast from their intensive internal medicine review course. Thyroid Disorders.

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