PrimeCuts

Cancer Immunotherapy: A Primer for Clinicians

June 5, 2018
Cancer Immunotherapy: A Primer for Clinicians

By Thatcher Heumann, MD

Peer Reviewed

The Next Big Thing

For many physicians in training, navigating through the numerous anti-cancer agents and keeping pace with the latest treatments can be daunting. Major categories of systemic cancer treatments include chemotherapy (cytotoxic drugs that arrest the cell cycle), hormonal therapy (drugs that inhibit hormone production or bind to ‘starve’ cancers that thrive off of estrogen/testosterone), and targeted therapy (small molecules or monoclonal antibodies that bind to intra/extracellular targets to block tumor angiogenesis/growth factor signal transduction, or mark …

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Primecuts- This Week in the Journals

May 22, 2018
Primecuts- This Week in the Journals

By Kevin Zhang, MD

Peer Reviewed

This last week saw yet another school shooting when a student in Texas opened fire on his classmates, killing 10, fueling the ongoing debate about our nation’s gun laws as well as skepticism that any meaningful action would be taken to prevent future tragedies. Perhaps the most poignant comment in came from satirical news site The Onion who wrote, ‘No Way To Prevent This,’ Says Only Nation Where This Regularly Happens.

On the other side of the Atlantic, Meghan …

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Primecuts – This Week in the Journals

May 15, 2018
Primecuts – This Week in the Journals

By Michael Tamimi, MD

Peer Reviewed

At a mere 104 years old, famed ecologist and botanist David Goodall, who was frequently touted as Australia’s oldest scientist, ended his own life via assisted suicide in Switzerland with family and friends at bedside. A proponent of Exit International, Dr. Goodall, just prior to his death, spoke about how he “regret reaching that age,” and noted the “sadness” attributed to his wishes, is not sadness in the desire to die, but rather the fact that “one is prevented” …

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Primecuts-This Week in the Journals

May 1, 2018
Primecuts-This Week in the Journals

Mother Spring has arrived in New York this week and she is lovely. Flowers are blooming, birds are tweeting, rodents are merrily scurrying to and fro in full view just as we humble folk have at long last emerged from our musty hovels to share the majesty of this sun-drenched city nestled between the fresh waters of the Hudson and the salty straits of the East.

With this sense of beauty and appreciation in mind, let us now turn our attention to medicine, and to …

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Primecuts – This Week in the Journals

April 24, 2018
Primecuts – This Week in the Journals

By Jennifer Whealdon, MD

Peer Reviewed 

Prior to her passing, former First Lady Barbara Bush announced her decision to forego further aggressive interventions for her chronic medical issues and instead elected for “comfort care”, to spend the final days of her life at home with her loved ones(1).  Her courageous decision revitalized discussion about how we approach end of life care in the United States. Particularly, by publicizing her decision to forego further invasive treatment, she exemplified a thoughtful and intentional consideration for what constitutes …

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Primecuts – This Week in the Journals

April 3, 2018
Primecuts – This Week in the Journals

By Maya Madhavan, MD

Peer Reviewed

Last week, over a people million took to the streets to march for gun control as part of the March for Our Lives movement. It was noted to be one of the biggest youth protests since the Vietnam War1. Across the nation, medical students and housestaff also participated in institution wide protests and discussions, as many consider gun-related violence to be a public health crisis. Let’s take a look at what else went on in the medical community over …

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Primecuts – This Week in the Journals

March 27, 2018
Primecuts – This Week in the Journals

By Lauren Yokomizo, MD

Peer Reviewed

One of the most underappreciated aspects of the current opioid epidemic is over prescribing in the elderly. In 2016, one in three patients on Medicare, approximately 14.4 million patients, was prescribed opioids. As part of the federal government’s response to the opioid epidemic, Medicare will no longer pay for long term, high dose opioid prescriptions. The new regulation is expected to take effect April 2nd. The rule has been met with a divided response. Supporters praised it as a …

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Smoking Cessation: Are all Modalities the Same?

March 22, 2018
Smoking Cessation: Are all Modalities the Same?

By  Monil Shah, MD

Peer Reviewed

Each year around 6 million people are killed by tobacco worldwide.1 Tobacco remains a leading preventable cause of death worldwide.2 From 1965 to 2010, the prevalence of cigarette smoking in the United States has declined from 42.4% to about 19%. This decline is mainly due to public awareness regarding harmful effects of smoking, increase in prices of tobacco products, and implementation of smoke-free policies.3 Despite tremendous strides made in raising public awareness regarding the adverse health effects of smoking …

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