PrimeCuts

PrimeCuts: This Week in the Journals

September 14, 2009
PrimeCuts: This Week in the Journals

Michael Ford MD

Faculty Peer Reviewed

Last┬áspring, The New York Times published a series of articles that examined the status of “the War on Cancer,” initiated some 40 years ago by then president Richard Nixon. The halting pace of this war was made more poignant with the recent death of Senator Edward M. Kennedy, who had championed the effort from its inception. Certainly, much has been learned about cancer in the intervening decades, but while other illnesses saw dramatic…

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Primecuts-This Week in the Journals

September 7, 2009
Primecuts-This Week in the Journals

Robert Gianotti, MD

Labor Day is upon us and the summer is now officially over…and what a summer it has been! The entire world was gripped with fears of H1N1, we lost two iconic figures from the political and pop worlds, and we saw the Yankees surge into first place behind Derek Jeter and his 2,713 career hits. As our tans fade, and the days shorten I thought it was time to get back to the “heart” of the matter and…

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PrimeCuts: This Week in the Journals

August 31, 2009
PrimeCuts: This Week in the Journals

Christina Adaniel MD

Faculty peer reviewed

The country mourned over the loss of Senator Kennedy this week, 15 months after his diagnosis with malignant glioma. As plans for healthcare reform undergo increasing scrutiny and the American public becomes ever more disillusioned, Mr. Kennedy’s passing reminds us of his vision for a nation in which “every American…will have decent, quality healthcare as a fundamental right and not a privilege.”Healthcare policy, however, seems to move in the opposite direction of science.…

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PrimeCuts: Week of August 24th

August 24, 2009
PrimeCuts: Week of August 24th

Jon-Emile Kenny

Faculty Reviewed

Roughly 40,000 women die each year in the United States from breast cancer, and nearly 200,000 will be newly diagnosed; we have all been affected by this disease, and this week’s PrimeCuts looks at the latest in the treatment, diagnosis and molecular pathophysiology of this common malignancy.

Four years ago, the BIG 1-98 study compared, tamoxifen monotherapy and aromatase inhibitor monotherapy (letrozole) among postmenopausal women with receptor-positive breast cancer. This early study revealed that aromatase inhibitor given alone, as compared with…

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Primecuts-This Week in the Journals

August 17, 2009
Primecuts-This Week in the Journals

Ivan Saraiva, MD

Faculty peer reviewed

This week’s edition of PrimeCuts will focus on an old friend, influenza, as well as a couple of other viruses. The novel swine-origin influenza A (H1N1) pandemic has no signs of decreasing its intensity. The New York Times reports on the pandemic reaching India, with nearly 1,200 cases and at least 17 deaths reported thus far. As the flu spreads in the southern hemisphere, the US prepares for a resurgence this fall.…

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PrimeCuts: This Week in the Journals

August 10, 2009
PrimeCuts: This Week in the Journals

Jeff Mayne MD

Faculty Peer Reviewed

This weeks PrimeCuts focuses on vertebroplasty for vertebral compression fractures, Clostridium difficile infection (CDI) misconceptions, and the efficacy of screening for intimate partner violence. Vertebroplasty is performed by injecting an acrylic cement into the collapsed vertebral body. On August 6th, the New York Times reported that last year, about 73,000 Americans had the treatment, which costs $2,500 to $3,000…and that results from new studies indicate the procedure is “no better than placebo.” The two articles…

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PrimeCuts: This Week in the Journals

August 3, 2009
PrimeCuts: This Week in the Journals

Michael Chu MD

Faculty Peer Reviewed

With summer well underway and a new class of interns having gotten their feet wet by now (perhaps it might feel more like drowning for a few), we have a few interesting articles in the news this past week, ranging from black-market organ sales in the US to immunodeficiency viruses in chimpanzees.

This past week the press reported on an FBI probe into corruption charges in New Jersey involving mayors and…

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PrimeCuts- This Week in the Journals

July 27, 2009
PrimeCuts- This Week in the Journals

Onyeka Okonkwo MD

Faculty peer reviewed

Alzheimer’s disease (AD) is the most common cause of dementia affecting over 4.5 million Americans, with cases in the US projected to triple over the next 40 years in the absence of advancements in therapy. With the aging of the American population, the disease has become an increasingly significant source of healthcare spending, with over 80 billion dollars dedicated annually to the care of patients with Alzheimer’s. Consequently, a number of research…

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PrimeCuts: This Week in the Journals

July 20, 2009
PrimeCuts: This Week in the Journals

Farshid Yazdi MD

Faculty Peer Reviewed

In America, we are quickly coming upon a moment in history that will likely affect us for decades to come. A recent article in the New York Times describes the upcoming health care bill as one that will transform our health care system. President Obama has vowed to have these bills passed before the summer sessions end, but some in Congress are apprehensive about releasing such a major bill so quickly. With 45…

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PrimeCuts: This Week in the Journals

July 13, 2009
PrimeCuts: This Week in the Journals

Ami Jhaveri MD

Faculty Peer Reviewed

A low calorie diet, high adiponectin levels, new anti-cancer agents, and for patients on erythropoietin, hemoglobin levels between 9-12 g/dL are on the prescription pad this summer.

The New York Times reported that a low calorie diet may extend life in primates. Researchers at the University of Wisconsin have been studying rhesus monkeys and the effects of low calorie diets on their health and mortality. As the average lifespan of rhesus…

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PrimeCuts: This Week in the Journals

July 6, 2009
PrimeCuts: This Week in the Journals

Ishmeal Bradley MD

Faculty Peer Reviewed

Let’s face it, the American population is getting older. With the graying of our populace (life expectancy 80 years for females, 74 for males), there has come an increased need for better quality of care and more cost-effective preventive care. The current healthcare fiscal crisis only highlights the need to more carefully spend our healthcare dollars. This week, the journals spent considerable space discussing the particular needs of the elderly and the preventive…

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PrimeCuts: This Week in the Journals

June 29, 2009
PrimeCuts: This Week in the Journals

Sarah Moore MD

Faculty peer reviewed

If you’ve seen the news or even the cover this week’s Economist on newsstands (Obama as surgeon with a very large needle promising that yes, it’s going to hurt- a lot), you may think that healthcare in the U.S. is all about the money. In keeping with this theme the journals this past week have included a flurry of Markov models and QALY’s to answer the same question- is it worth it?…

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