Not So Rosi…

May 24, 2007

Commentary by Seagram Villagomez MD, Chief Resident

Since its approval in 1999, nearly 1 million Americans have used the thiazolidinedione (TZD) rosiglitazone (Avandia – GlaxoSmithKline) for the treatment of Type 2 Diabetes.  However, in a drug class which seems plagued by…

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Posted in Endocrine, Journal Club, Pharmacology

How Do You Estimate Stroke Risk After a Transient Ischemic Attack?

April 24, 2007

BrainBy: Alana Choy-Shan, MD PGY-3
Transient ischemic attacks (TIAs) are known to be a harbinger of stroke, however it is difficult for physicians to estimate individual stroke risk. Previously, the two systems used to predict short-term risk of stroke after a…

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Posted in Journal Club, Neuro

New Guidelines on the Diagnosis and Treatment of Venous Thromboembolism-Part 1

April 12, 2007

800px-parque_del_clot_03.JPGCommentary By: Margaret Horlick, MD, PGY-3

New guidelines on the diagnosis and treatment of venous thromboembolism (VTE) were recently jointly issued by the American Academy of Family Physicians and the American College of Physicians. The guidelines are based on a systematic…

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Posted in Heme/Onc, Journal Club, Pulmonary/Critical Care

Does Screening for Lung Cancer Improve Mortality?

April 10, 2007

Spiral CTCommentary By: Anna Dvorak, MDPGY-3

Lung cancer is the number one cause of cancer mortality in both men and women. Screening patients at risk for lung cancer might reduce mortality if it helps find cancers at an early stage while they…

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Posted in Journal Club, Pulmonary/Critical Care

Does the Overuse of Macrolides Lead to Antibiotic Resistance?

March 12, 2007

MortarCommentary By: Danise Schiliro, PGY-3

Although intuitively we always worry about creating drug resistance when using antibiotics, there is a surprising lack of well done studies that show a clear causal effect of antibiotic use on the development of subsequent drug…

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Posted in ID, Journal Club, Pharmacology

Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy?

February 16, 2007

Endoscope

Commentary By: Joshua Olstein PGY-3

Second only to lung cancer, colon cancer claimed an estimated 55,000 lives in the United States in 2006. In an effort to reduce colon cancer morbidity and mortality, multiple screening tests have been developed to detect…

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Posted in GI, Journal Club

A drug for NASH that may work?

January 24, 2007

Commentary By: Sandra D'Angelo, PGY-3

Nonalcoholic steatohepatitis (NASH) is a disease in which patients have features of alcoholic hepatitis on liver biopsy without a prior history of significant alcohol consumption and negative hepatitis serologies. It is unclear how prevalent this disease…

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Posted in GI, Journal Club

Should we recommend mammography screening for women between the ages of 40-50?

December 22, 2006

In a recent article in the Lancet, this question was addressed by a group of investigators led by Sue Moss, Ph.D. from the University of Leeds.  Currently, the  National Cancer Institute, U.S. Preventative Health Services Task Force and the American…

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Posted in Heme/Onc, Journal Club

Should You Recommend Surgery or Conservative Care for Disc Herniation?

November 29, 2006

In the November 22nd issue of JAMA, the results of two studies from the Spine Patient Outcomes Research Trial (SPORT) on lumbar disk surgery for persistent radicular pain are reported.  Both these studies sought to assess the efficacy of surgery…

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Posted in Journal Club, Neuro

Epogen and Anemia-Less is More

November 17, 2006

Singh AK et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006 Nov 16; 355:2085-98.

Drüeke TB et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 2006…

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Posted in Journal Club, Renal

NYU’s Dr. Hochman Releases OAT Results

November 16, 2006

                          Hochman JS et al. for the Occluded Artery Trial Investigators. Coronary intervention for persistent occlusion after myocardial infarction. N Engl J Med 2006 Nov 14; 355.

Reperfusion via thrombolytics or PCI in patients with acute STEMI has been shown to reduce…

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Posted in Breaking News, Cardiology, Journal Club