The big bomb this past week was the Rosiglitazone Effect. Resulting in front page news in various newspapers (on multiple days), the meta-analysis in last week’s NEJM is causing quite the stir. For more information, see …
Author: Neil.Shapiro@nyulangone.org
Clinical Correlations
How should you approach a pregnant patient with chronic kidney disease?
May 25, 2007
A 31 year old female with hypertension and proteinuria secondary to IgA nephropathy, currently treated with an ARB, presents to clinic stating that she would like to become pregnant.
What is the risk of fetal morbidity in the setting …
FDA Black Box Warning on Gadolinium
May 24, 2007Back in December we reported on the FDA cautioning practioners about the use of gadolinium (an mri contrast agent) in patients with chronic kidney disease.  The FDA is now requesting a black box warning  stating “that patients with severe kidney insufficiency who receive gadolinium-based agents are at risk for developing a debilitating, …
Not So Rosi…

Commentary by Seagram Villagomez MD, Chief Resident
Since its approval in 1999, nearly 1 million Americans have used the thiazolidinedione (TZD) rosiglitazone (Avandia – GlaxoSmithKline) for the treatment of Type 2 Diabetes. Â However, in a drug class which …
ShortCuts-This Week in the Journals
May 21, 2007
This week’s review is a potpourri of interesting if not groundbreaking articles.
The pharmaceutical industry certainly got off easier this week (see last week’s shortcuts) and the New York Times focused instead on the “industrialization†of the art of medicine. A hospital …
Clinical Pathology Conference 5/11/07-The Answer
May 18, 2007Please review the posting of last week’s CPC Case here.
When you’re ready you can download the CPC Answer here.
Clinical Pharmacy Corner-The Thiazides
May 17, 2007Â We’d like to introduce you to Clinical Correlations’ newest feature-Clinical Pharmacy Corner. This will be a bimonthly pharmacy themed post which will tackle both basic and complicated pharmacy issues. We will review the mechanisms of actions of various classes of medications, a worthwhile refresher for those of us …
Mystery Quiz #3-The Answer
May 15, 2007Before you read the answer you should read the orginal post form last week
The Final Poll Results (26 votes): metastatic disease (26%) , mycobacterial disease (22%) ,fungal disease (22%), bronchiolitis obliterans with organizing pneumonia (boop) (13%), septic emboli (9%) ,vasculitis, e.g. wegener’s (4%), thromboembolic disease (4%), sarcoid (0%)