How Do You Approach A Patient with a Non-Ischemic Cardiomyopathy

March 7, 2007
How Do You Approach A Patient with a Non-Ischemic Cardiomyopathy

A 26 year old woman developed uncontrolled hypertension peripartum 5 years prior to this presentation After diagnosis she was intermittently compliant with her medication although remained asymptomatic. She now presents with new onset congestive heart failure. On admission, she was in mild respiratory distress. Her physical exam was notable for tachycardia with a blood pressure ranging from 160/100-200/110. She had a jugular-venous pressure of 8cm, +S4, crackles were present bilaterally 1/2 way up, but no peripheral edema. Labs were notable only for renal insufficiency…

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More Breaking News: Rosiglitazone Linked to Fractures

March 6, 2007
More Breaking News: Rosiglitazone Linked to Fractures

Commentary By: Cara Litvin PGY-3

The FDA recently informed physicians of a report issued by GlaxoSmithKline acknowledging that Avandia (rosiglitazone) has been linked to increased fractures in females (1). The report stems from a review of the safety data from ADOPT (A Diabetes Outcome and Progression Trial) (2), which was a recently published randomized trial of 4,360 patients designed to compare glycemic control with rosiglitazone relative to metformin and glyburide monotherapies. In the published study, there were no unexpected adverse events reported, although…

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Gone Fishin’

February 23, 2007
Gone Fishin’

Due to vital conflicting commitments (vacation), Clinical Correlations will be closed until March 6th when we will resume posting new content. This is the perfect opportunity to catch up on our previous content and to think about what you’d like to see on clinical correlations in the future. Search by date or by category with the toolbar at the right of this post. As always send us any comments or feedback to clinicalcorrelations@gmail.com. Have a great week.

Fishing from Wikipedia

Vacation from Wikipedia

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The Vioxx Wars

February 23, 2007
The Vioxx Wars

Commentary By: Sandeep Mangalmurti MD, JD PGY-1

The continuing legal battles over Vioxx remain at the center of a fascinating intersection of law and medicine. Most physicians are well acquainted with the basics of the case, but like most complicated health care issues, the deeper one probes, the more interesting it becomes.

The Vioxx saga begins in 2000, with the VIGOR trial. (1) This study was a randomized control trial comparing the gastrointestinal toxicity of Vioxx to naproxen, and was notable for…

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Safety of Long-Acting Beta-Agonists in the Treatment of Asthma: Should they be used?

February 21, 2007
Safety of Long-Acting Beta-Agonists in the Treatment of Asthma: Should they be used?

Commentary By: Sarah Huen, PGY-3 and David Chong, Director of Critical Care, Bellevue Hospital, Associate NYU Internal Medicine Residency Program Director

The role of long-acting b-agonists (LABAs) in the treatment of asthma continues to be controversial. Growing evidence that LABAs may cause an increased risk of asthma exacerbations and asthma-related deaths prompted the U.S. Food and Drug Administration (FDA) to approve “black box” safety warning labels for Serevent Diskus (salmeterol xinafoate), Advair Diskus (fluticasone propionate; salmeterol xinafoate), and Foradil (formoterol fumarate). Concern about…

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Evolution of a Blog-Clinical Correlations 2.0

February 20, 2007
Evolution of a Blog-Clinical Correlations 2.0

You may have noticed a few changes here at Clinical Correlations. First if you look at the top of the page we have a great new logo created by a professional graphics arts designer. Second, if you look just below the logo, there is now a link to a page entitled The Essential Reading Lists. This link takes you to a bibliography listing the essential articles as picked by our faculty members of the NYU Internal Medicine Curriculum Committee. The lists do not yet include…

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Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy?

February 16, 2007
Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy?

Commentary By: Joshua Olstein PGY-3

Second only to lung cancer, colon cancer claimed an estimated 55,000 lives in the United States in 2006. In an effort to reduce colon cancer morbidity and mortality, multiple screening tests have been developed to detect early disease among asymptomatic individuals. The 2003 American Gastroenterology Associations guidelines for screening asymptomatic individuals recommended colonoscopy as a preferred method of screening.

Due to a higher risk of colonic neoplasm, patients with unexplained iron-deficiency anemia are not included in these…

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PB&J Hold the P: Salmonella Outbreak Linked to Peanut Butter

February 15, 2007
PB&J Hold the P: Salmonella Outbreak Linked to Peanut Butter

Commentary By: Cara Litvin PGY-3

 

The CDC has issued a public health advisory regarding a large outbreak of Salmonella infections in 39 states since August. As of Tuesday February 14, 288 cases had been reported to the CDC. Among the 120 patients for whom clinical information is available, 31 patients have been hospitalized, and no deaths have been reported. The most cases have been reported in New York, Pennsylvania,…

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