Are We Overusing Proton Pump Inhibitors?

November 13, 2015
Are We Overusing Proton Pump Inhibitors?

By Shimwoo Lee
Peer Reviewed
Case: A 31-year-old man with poorly controlled type 2 diabetes was hospitalized for community-acquired pneumonia. His home medications included esomeprazole. When asked why he was receiving this medication, the patient said it was first started during his prior hospitalization for “ulcer prevention” eight months ago and that he had continued to take it since. He denied any history of upper gastrointestinal symptoms. Esomeprazole was tapered off during this admission. When being discharged after successful treatment of his pneumonia, he was …

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Primecuts-This Week in the Journals

November 10, 2015
Primecuts-This Week in the Journals

By: Loren Franco, MD

Russia has suspended all flights to Egypt amidst mounting reports and evidence that a terrorist bomb took down the Metrojet flight to St. Petersburg. Last week on October 31st, a Metrojet plane carrying 224 individuals exploded soon after taking off in a resort town in Egypt on its way to St. Petersburg, killing everyone on board. Soon after the news hit, ISIS affiliates began to take credit for the crash but never described how it was done, prompting authorities to question …

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Primecuts-This Week in the Journals

November 3, 2015
Primecuts-This Week in the Journals

By Stephanie Wu, MD

Peer Reviewed

This past weekend, we cheered for the 50,000 people who ran the NYC marathon. Jonathan Mendes, at 94 years old, tackled this marathon for his 14th time . In the midst of this momentous and triumphant occasion, we witnessed the tragic loss of 224 people on board a plane that crashed in Egypt. Earlier in the week, China repealed its one-child policy that had been in place since 1979. With plenty of Halloween candy in our stomachs and an …

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Supporting Evidence

October 30, 2015
Supporting Evidence

By: Amy Ou

During a weekend off at my parents’ home, the subject of this chronic cough that I had developed for the entirety of the winter season came up. My mother, noticeably more concerned about it than I, asked: “Did you get a flu shot? Did you get your cough after you got your flu shot? You know this happened when you were little, right? I just don’t know about those flu shots, I think they have some bad side effects. Your dad and …

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Primecuts-This Week in the Journals

October 27, 2015
Primecuts-This Week in the Journals

By: Rory Abrams, MD

This past week the Mets became the 2015 National League Champions and are headed to the World Series. Larry David stole our hearts and minds after his impersonation of Bernie Sanders on SNL. Joe Biden officially announced he is not running for President in 2016. And Nike announced it will manufacture a limited number of the self-lacing shoes from Back To The Future 2, which will be auctioned off to raise money for Parkinson’s Disease research and the Michael J. Fox …

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Primecuts-This Week in the Journals

October 19, 2015
Primecuts-This Week in the Journals

By Abinav Baweja, MD

This past week we witnessed the first democratic national debate, where Hillary Rodham Clinton quieted doubters with her strong showing and minimized talk regarding her e-mail account. Meanwhile, ex-NBA player Lamar Odom was found unconscious in a brothel in Las Vegas where he had been using herbal analogs of Viagra and cocaine, and is presently in critical condition. Amidst all this news, we move on to some of the latest findings in the medical literature…

Is remote ischemic preconditioning beneficial for

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Beta-blockers in Uncomplicated Hypertension: Is it Time for Retirement?

October 7, 2015
Beta-blockers in Uncomplicated Hypertension: Is it Time for Retirement?

By Robin Guo, MD

Peer Reviewed 

Beta-blockers were one of the first modern medications used for the treatment of blood pressure. Before 1950, treatment options for hypertension were limited. The alphabet soup of medications—reserpine, pentaquine, hydralazine, and guanethidine—were notorious for inducing orthostasis, sedation, constipation, impotence, or blurry vision . Then in the 1960s, propranolol and chlorothiazide were developed. Initially designed to treat angina pectoris, propranolol was serendipitously discovered to also lower blood pressure. Oddly, propranolol, like the other beta-blockers in its generation and thereafter, did …

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Primecuts – This Week In The Journals

October 5, 2015
Primecuts – This Week In The Journals

Olivia Begasse de Dhaem, MD

Peer Reviewed  

Last month, Turing Pharmaceutical bought the rights to pyrimethamine, also known as Daraprim, and subsequently raised its price significantly (from $13.5 to $750 per tablet). Unlike Rodelis Therapeutics who gave back cycloserine when facing resistance, Turing Pharmaceuticals are determined to keep their newly increased price for Daraprim. The new trend in the pharmaceutical world of acquiring old medications and increasing their prices has led to controversy on whether the government should take action in regulating pharmaceutical prices and …

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