By Ishmeal Bradley, MD
Faculty Peer ReviewedÂ
The goal of public health is to prevent or minimize disease and injury on a population level. How to achieve this end has changed over …
Category: Pharmacology
Clinical Correlations
Medicine By Numbers: 131 Million
October 28, 2011
By Maryann Kwa, MD
Faculty Peer Reviewed
131 million: The number of times the most popular medication in the United States was prescribed in 2010.
Recently, IMS Health, a company that monitors annual sales for pharmaceutical and healthcare industries, published a list …
They’re all the ‘roid rage: origins and mechanisms of corticosteroid therapy.
September 23, 2011
By Santosh Vardhana, MD
A 36-year-old obese male with hypertension and hyperlipidemia presents to the ER with new knee pain, swelling, and erythema. Joint aspiration reveals negatively birefringent crystals. He is started on oral prednisone.
A 26-year-old woman with lupus presents …
Avastin and the Meaning of Evidence
September 9, 2011
By Antonella Surbone MD PhDÂ and Jerome Lowenstein MD
The recent hearings at the Food and Drug Administration regarding the revocation of approval for the use of Avastin in the treatment of breast cancer [1,2,3] bring into sharp focus several …
More Pills, More Problems: The Polypill Revisited
August 3, 2011
By Jonathan Leventhal
Faculty Peer Reviewed
Polypharmacy has become an integral part of daily life for millions of chronically ill patients worldwide, and rightfully so. Evidence-based studies have repeatedly demonstrated that multiple drugs are required for optimal therapeutic management in chronic …
Low Dose Vitamin K Supplementation and Anticoagulation Control
July 21, 2011
By Joanna Becker
Faculty Peer Reviewed
Patients who are placed on long-term warfarin (Coumadin) therapy are sent home with a lengthy list of restrictions to minimize variations in warfarin efficacy. The agents that can alter warfarin levels can be divided …
Breaking News: FDA issues new dosing limitations for Simvastatin
June 10, 2011
By Saleem Ali, MD
The FDA has issued new warnings regarding the use of high dose Simvastatin. The FDA is now recommending that the 80mg dose only be used in patients who have been taking that dosage for at least …
Resveratrol: The Modern Fountain of Youth?
February 9, 2011
By Lee Rasamny
Faculty Peer Reviewed
For thousands of years, humans have been fascinated with the idea of slowing and perhaps even reversing the process of aging. From Ponce de León to modern …