Systems

Grand Rounds: “Novel Applications of Erythropoietin in Cardiovascular Disease”

October 22, 2008
Grand Rounds: “Novel Applications of Erythropoietin in Cardiovascular Disease”

Commentary by Srikant Duggirala MD, PGY-2

Please also see the clinical vignette presented during this week’s grand rounds

 

On Wednesday, October, 15, 2008, the NYU Department of Medicine Grand Rounds featured one of its own guest speakers, Stuart Katz M.D., Professor of Medicine and Director of Heart Failure at NYU School of Medicine, with his lecture entitled “Novel Applications of Erythropoietin in Cardiovascular Disease.”

Dr. Katz began his lecture with a discussion of oxygen uptake in a various individuals such as elite…

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Grand Rounds: “Molecular Genetics of Colorectal Cancer”

October 19, 2008
Grand Rounds: “Molecular Genetics of Colorectal Cancer”

Commentary by Sabina Berezovskaya MD PGY-3

Please also see the clinical vignette presented during last week’s grand rounds

On Wednesday, October 8, 2004, the NYU Department of Medicine Grand Rounds featured guest lecturer Vincent Yang, M.D. Ph.D., Professor of Medicine and Director of  Division of Digestive Diseases at Emory University School Medicine with a presentation entitled  “Molecular Genetics of Colorectal Cancer”.

 

Dr. Yang first oriented the audience to the outline of the talk and began his presentation with a case…

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Class Act: Is there clinical evidence for the use of chondroitin sulfate in the treatment of osteoarthritis?

October 17, 2008
Class Act: Is there clinical evidence for the use of chondroitin sulfate in the treatment of osteoarthritis?

Class act is a feature of Clinical Correlations written by NYU 3rd and 4th year medical students. Prior to publication, each commentary is thoroughly reviewed for content by a faculty member.

Commentary by Jillian Borman, MS-4, Reviewed by Svetlana Krasnokutsky, MD, Clinical Instructor, NYU Department of Medicine

Osteoarthritis (OA) is one of the most common causes of joint pain in the aging population. The pain of OA, which is generally worsened with joint use and alleviated with rest, is typically described as a deep…

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Grand Rounds: “Behcet’s Disease: What It Is, and Isn’t”

October 16, 2008
Grand Rounds: “Behcet’s Disease: What It Is, and Isn’t”

Commentary by Jon-Emile Kenny MD, PGY- 2

Please also see the clinical vignette presented during last week’s grand rounds

Dr.  Yusuf Yazici of the NYU Behcet’s Syndrome Center opened his talk by discussing the classic triad of symptoms characteristic of Behcet’s Disease: aphthous ulcers, genital ulcers and uveitis.  This was originally characterized by the Turkish physician Hulusi Behcet in 1937.  While these symptoms are the most common of Behcet’s, other tissues may be affected as Behcet’s is a systemic vasculitic disorder.  GI symptoms, neurological sequelae, the pathergy…

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Breaking News: USPSTF Recommends Against Routine Screening for Colorectal Cancer After Age 75

October 8, 2008

Commentary by Andrew McKinstry MD, PGY-1 (reviewed by Michael Poles, MD, Associate Editor Clinical Correlations, Assistant Professor of Medicine, Section of Gastroenterology)

Hot on the heels of its recommendation in August against routine screening for prostate cancer in men over 75, the US Preventive Services Task Force has issued recommendations against routine screening for colorectal cancer in patients over the age of 75- Yes, you read that correctly, NO routine screening for colorectal cancer past age 75.  In a report updating their recommendations from 2002, the…

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Grand Rounds: Clinical Development of Anti-Cancer Drugs: Succeed Slowly or Fail Fast

October 3, 2008
Grand Rounds: Clinical Development of Anti-Cancer Drugs: Succeed Slowly or Fail Fast

Commentary by Daniel Egan MD, PGY2

Please also see the clinical vignette presented during last week’sgrand rounds

On Wednesday, September 24, 2008, the NYU Department of Medicine Grand Rounds featured guest speaker Hilary Calvert, MD, Professor of Medical Oncology at the University of Newcastle upon Tyne, England, with a lecture entitled “Clinical Development of Anti-Cancer Drugs: Succeed Slowly or Fail Fast.”

Dr. Calvert first oriented the audience by reviewing the traditional method in which new chemotherapeutic drugs have been developed and introduced to the…

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Propofol Infusion Syndrome: An Unusual Case of Lactic Acidosis

October 1, 2008
Propofol Infusion Syndrome: An Unusual Case of Lactic Acidosis

Commentary by Bani Chander MD, PGY-3 and Reviewed by Laura Evans MD, NYU Division of Pulmonary and Critical Care Medicine

Case presentation:

The patient is a 26 year-old female with long-standing refractory epilepsy, status post corpus callosotomy, and vagus nerve stimulator placement, who was admitted to the intensive care unit for management of status epilepticus. The patient was initially admitted to the inpatient epilepsy unit and placed on multiple anti-epileptic medications with little response. However, after having more than ninety seizures over the…

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Mystery Quiz- The Answer

September 27, 2008
Mystery Quiz- The Answer

Posted by Vivian Hayashi MD and Robert Smith MD,

Mystery Quiz Section Editors

The answer to last week’s mystery quiz is pneumatocele/pseudocyst likely due to ventilator associated lung injury (VALI) in a patient with ARDS. The patient had

ARDS on the basis of diffuse infiltrates, hypoxemia with a PaO2/FiO2 <200mmHg, and no strong evidence of LV heart failure. His risk factor for ARDS was pneumonia, evident on his admission CXR with bibasilar infiltrates (R>L); Streptococcus pneumoniae grew on sputum culture. The…

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Meeting Perspectives: The ADA Scientific Sessions: Advances in the Pharmacologic Management of Type 2 Diabetes Mellitus

September 25, 2008
Meeting Perspectives: The ADA Scientific Sessions: Advances in the Pharmacologic Management of Type 2 Diabetes Mellitus

Commentary by  Howard Furst MD and Mitchell Charap MD

We will focus our review of the 2008 ADA meetings on new data regarding the GLP-1 analogues and the DPP 4 inhibitors. Before describing the clinical data, we will review the basic science that led to interest in these new classes of drugs for the treatment of diabetes mellitus.

Background
Incretins are peptides released from the gastrointestinal tract in response to nutrient ingestion. They enhance glucose-dependent insulin secretion from the pancreas and aid in…

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Grand Rounds: Thyroid Disease and the Heart

September 24, 2008
Grand Rounds: Thyroid Disease and the Heart

 Commentary by Sarika Modi MD, PGY-2  

Dr. Irwin Klein MD, Professor of Medicine and Cell Biology, of North Shore University Hospital, gave grand rounds on “Thyroid Disease and the Heart” on September 17, 2008.  He began his talk by giving an overview of the broad spectrum of cardiac manifestations seen in hyperthyroidism.  Palpitations are seen in 90% of patients with hyperthyroidism.  Atrial fibrillation is seen in 5-15%, especially in the elderly.  In fact, as Dr Klein pointed out, former president George Bush Senior was…

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Mystery Quiz

September 19, 2008
Mystery Quiz

Posted by Vivian Hayashi MD and Robert Smith MD, Mystery Quiz Section Editors

The patient is a 76 year old man with history of moderate-to-severe COPD who presented with three days of fever, breathlessness, and productive cough. Past surgical history is significant for vagotomy and partial gastrectomy 16 years earlier and a cholecystectomy 10 months prior to admission. On exam, the patient appeared acutely ill with a blood pressure of 75/45 mmHg, tachycardia, marked hypoxemia and course breath sounds throughout all lung fields. Labs revealed a white…

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Grand Rounds: “Acute Respiratory Distress Syndrome and Acute Lung Injury”

September 17, 2008
Grand Rounds: “Acute Respiratory Distress Syndrome and Acute Lung Injury”

Commentary by Matthias Kugler MD, PGY-3

Please also see the Grand Rounds Clinical Vignette

Leonhard D Hudson, M.D., Professor of Medicine, Pulmonary and Critical Division, University of Washington, Seattle, spoke at Medical Grand Rounds about the Acute Respiratory Distress Syndrome (ARDS) and Acute Lung Injury (ALI). He started his lecture with a history of the disease, starting with the first published description of ARDS in The Lancet 1967, where it was defined by the presence of diffuse alveolar damage, increasing pulmonary…

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