By Elana Kreiger-Benson
Peer Reviewed
“I’m not actually planning to try it,” the patient whispered to me while I was feeling her radial pulses. We had just finished an extensive conversation with her primary care physician …
Category: Endocrine
Clinical Correlations
Inpatient Diabetes: Is There a Role for Metformin?
October 10, 2019
By Jamie Oliver
Peer Reviewed
“Hold metformin, start sliding-scale insulin, diabetic diet, subcutaneous heparin.”
Just 10 words. For almost all admitted type 2 diabetics receiving metformin, this 10-word phrase is automatic. I am sure many medical students …
On the History of Statins
January 11, 2019
By David Pineles, MD
Peer Reviewed
With the implementation of the ACC/AHA guidelines on assessment of cardiovascular risk, HMG-CoA reductase inhibitors, commonly known as statins, will become one of the most prescribed medications in history [1]. Dr. John Ioadnnidis, in an article published in JAMA …
Spotlight: A case of Metformin Associated Lactic Acidosis
May 11, 2018
By Jasmine Nee and Martin Fried, MD
Peer Reviewed
LEARNING OBJECTIVES
1. What is metformin-associated lactic acidosis?
2. How does severe acidemia lead to acute kidney injury?
3. How do you treat metformin-associated lactic acidosis?
CASE SUMMARY
The patient …
Insulin in a Pill: Barriers to Development of Oral Insulin
May 8, 2018
By Nicolas Gillingham
Peer Reviewed
Over 30 million Americans—9.4% of the population—live with diabetes, six million of whom are at least partially dependent on exogenous insulin.[1] Insulin can be self-administered by subcutaneous …
A Rare Complication of Diabetes: Diabetic Myonecrosis
March 29, 2018
By Allison Harrington, MD
Peer Reviewed
Learning Objectives:
1) When should diabetic myonecrosis be suspected?
2) What are the diagnostic criteria for diabetic myonecrosis? What is the pathophysiology?
3) What is the management of diabetic myonecrosis? How can it be …
How Reliable Is Hemoglobin A1c?
April 6, 2017
By Alexa Yuen
Peer Reviewed
According to the CDC, there are 22 million people with an established diagnosis of diabetes mellitus in the United States, but more frightening is that the rate of …
Gamechanger? Can Pioglitazone Reduce Cardiovascular Events After a Stroke? An Analysis of the IRIS Trial
January 19, 2017
By Johanna Hase, MD
Peer Reviewed
Welcome to Gamechangers, a series that takes a critical look at the latest in medical literature to answer one important question: would the results of this article …