From the Archives: Did Abraham Lincoln Have Marfan Syndrome?

April 13, 2017
From the Archives: Did Abraham Lincoln Have Marfan Syndrome?

Please enjoy this post from the archives dated April 19, 2013

By Anna Krigel Faculty Peer Reviewed The iconic image of Abraham Lincoln is ubiquitous in our lives, from his small face on the penny to his large figure looming over the National Mall in Washington, D.C. Lincoln fascinates historians because of his significant role in American history when our nation was bitterly divided, but he intrigues physicians because of his remarkable stature. A reporter once described the 16th president as a “tall, lank, lean…

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Oxygen Saturation Target of 88-92% in COPD: Evidence-based Medicine?

April 12, 2017
Oxygen Saturation Target of 88-92% in COPD: Evidence-based Medicine?

By Christopher V. Cosgriff

Peer Reviewed

The American College of Physicians (ACP) recommends supplemental long-term oxygen therapy (LTOT) in all patients who have severe resting hypoxemia, defined as a PaO2 ≤55 mmHg or an SpO2 ≤88%. In patients with cor pulmonale or polycythemia they recommend initiation of oxygen therapy at a PaO2 ≤59 mmHg.1 Absent from the ACP recommendation is a target range to which saturation should be restored. The accepted standard of practice is restoration to a range of 88%-92%, and there are British …

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Primecuts – This Week in the Journals

April 11, 2017
Primecuts – This Week in the Journals

Susan Creighton, MD

Peer Reviewed

Judge Neil M. Gorsuch was confirmed to the Supreme Court after Senate Republicans voted to lower the threshold required for Supreme Court nominations. Last week Senate Democrats used a filibuster to block the nomination, which would have required 60 votes before the rule change. At 49 years old, Justice Gorsuch could have a long tenure on the Supreme Court and shape the legal landscape for decades. Reproductive rights groups oppose Justice Gorsuch’s nomination because as part of the 10th Circuit …

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How Reliable Is Hemoglobin A1c?

April 6, 2017
How Reliable Is Hemoglobin A1c?

By Alexa Yuen

Peer Reviewed 

According to the CDC, there are 22 million people with an established diagnosis of diabetes mellitus in the United States, but more frightening is that the rate of diabetes continues to rise both nationally and globally, with predictions that 7.7% of the world’s adult population will be afflicted with the disease in 2030., Preventing, monitoring, and managing this disease is of utmost importance in responding to the growing epidemic. The hemoglobin A1c (HbA1c) blood test has become a powerful tool …

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Primecuts – This Week in the Journals

April 4, 2017
Primecuts – This Week in the Journals

By Jillian Diuguid, MD

Peer Reviewed

On Friday, March 31, New York City Mayor Bill de Blasio announced his support for a plan to shutter Rikers Island, the controversial East River island jail known for its history of violence by both inmates and corrections officers.  Per the Mayor, the closure plan will be complicated and difficult, taking 10 years, with significant reductions necessary in the number of jailed city inmates in order to make it possible.  The Mayor hopes this will be the end of …

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Book Review: in-Training: Stories from Tomorrow’s Physicians

March 31, 2017
Book Review: in-Training: Stories from Tomorrow’s Physicians

By Amar Parikh, MD

Peer Reviewed

“Wounded healers. It’s a concept…inspired by the story of Chiron, a centaur in Greek mythology who was renowned for his skills as a healer. Chiron was wounded by a poisoned arrow but his immortal status sustained him…He was thus condemned to spend eternity roaming the earth in agonizing pain, healing everybody but himself….the phenomena of depression and suicide among medical students and doctors suggest that we…fit into this archetype. “

The above selection is an excerpt from a moving …

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Why Does Our Hair Turn Gray?

March 30, 2017
Why Does Our Hair Turn Gray?

By Chio Yokose, MD and Aaron Smith, MD

Peer Reviewed 

All but a lucky few of us will one day see our locks lose their color. But what is the physiologic basis for this unsightly transformation, known scientifically as canities? Why does our hair turn gray?

Hair pigment is derived from the compound melanin, which is formed during melanogenesis in lysosome-like organelles called melanosomes, found in the cytoplasm of melanocytes . Melanocytes are ectodermal cells that migrate from the neural crest to the skin during …

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Primecuts – This Week in the Journals

March 28, 2017
Primecuts – This Week in the Journals

By Stephanie Charles, MD 

Peer Reviewed

This week marked an important point in our national health care debate. The American Health Care Act put forth by the Republican party failed to pass by Congress, allowing for the continuation of the Affordable Care Act, at least for now. Read below to learn of the important work published by the medical community this week. 

Trial of Pregabalin for Acute and Chronic Sciatica

Pregabalin (Lyrica, Pfizer) is an antiepileptic medication that has been shown to reduce symptoms of …

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